Cerebral leptomeningeal metastasis in a case of primary ovarian lymphoma
April 2010
A 38 years old female patient is presented who applied to our neurosurgery clinic due to symptoms such as headache, ataxia, vertigo, vomiting and complaints related to a mass at the back side of her head. The examination of cranial magnetic resonance imaging (MRI) of the patient displayed a mass which obliterates the transverse sinus and extends from the scalp to the epidural space at a certain...
An unusual presentation of non-Hodgkin lymphoma
March 2010
A 49 year old woman was admitted to our hospital with symptoms suggestive of breast cancer. The histological study of the left lumpectomy showed diffuse large B-cell lymphoma of the breast. In addition, the radiological assessment of the disease showed multiple organ involvement by the lymphoma. The patient achieved complete response after 3 cycles of chemotherapy but rapidly developed fatal evolution after the...
Silver binding nucleolar organiser regions in oral submucous fibrosis, lichen planus, leukoplakia and squamous cell carcinoma
December 2009
This study was undertaken to assess the biologic aggressiveness of sub mucous fibrosis, lichen planus, leukoplakia and squamous cell carcinoma of the oral cavity by determining the mean number of AgNORs and comparing them with those of normal mucosa. The study sample consisted of total 93 subjects. Biopsy specimens of 26 squamous cell carcinomas, 22 sub mucous fibrosis, 15 lichen planus, 15 leukoplakia and 15 healthy...
A case of breast cancer found as metastasis to the duodenum
December 2009
A 58-year-old woman underwent left total mastectomy for invasive ductual carcinoma of the breast in 2002. In November 2007, the upper gastrointestinal endoscopy showed that an ulcer (~ 0.3 × 0.5 cm) was covered with white fur and surrounded by edematus tissue at the anterior wall of duodenal bulb. The follow-up pathological examination revealed that the morphology of the cells of duodenal cancer was identical to...
Stage dependent expression of MUC1 glycoprotein in gallbladder carcinoma
October 2009
Gallbladder carcinoma is a relatively aggressive and frequently lethal cancer. It is defined as a clinicopathological presentation including a wide spectrum of lethal disease from simple gallstones to dysplasia, to carcinoma in situ and invasive carcinoma. MUC1, a cell surface antigen expressed in glandular epithelia, is overexpressed and aberrantly glycosylated in adenocarcinoma. In this report, the...
In vitro interaction of cyclooxygenase-2 inhibitors with radiation in nasopharyngeal carcinoma cell line: Dependence on sequence of administration
October 2009
In nasopharyngeal carcinoma (NPC), COX-2 inhibitors have been reported to exhibit dose-dependent growth inhibition of these cancer cells, but their interaction with radiation has not yet been studied. Here, we examined the effects of selective COX-2 inhibitors SC-236 and NS-398 on the radiosensitivity of NPC cells. When incubated with COX-2 inhibitors prior to ...
An improved implementation of brain tumor detection using segmentation based on soft computing
March 2009
Image segmentation is an important and challenging factor in the medical image segmentation. This paper describes segmentation method consisting of two phases. In the first phase, the MRI brain image is acquired from patients database, In that film, artifact and noise are removed after that HSom is applied for image segmentation. The HSom is the extension of the conventional self organizing map used to classify the...
The effect of using combination chemotherapy in colorectal cancer in India: A single institute survey
March 2009
The incidence of colorectal cancer in India is on upward swing due to the change in dietary habits. This study was done to evaluate the efficacy of two commonly used regimens. In this study, colorectal cancer patients treated with adjuvant chemotherapy from 1997 - 2001 were included and followed up for a period of five years. The efficacy of the commonly used regimens was compared in terms of five year disease free...
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