In vitro anti-infective and antioxidant activities of Garcinia cola Heckel and Morinda lucida Benth
August 2017
Garcinia cola also known as “bitter cola” (Guttiferae) is a plant with a wide usage of its parts for various medicinal purposes. The seeds are chewed as aphrodisiac and for the treatment of coughs, dysentery and liver inflammation. Morinda lucida (Rubiaceae) commonly called “great morinda” has been shown to have antimalarial and anti-pyretic activities. This study aimed at evaluating the...
Antibacterial activity of Datura stramonium against standard and clinical isolate pathogenic microorganisms
August 2017
Datura stramonium more commonly known as Jimson weed or thorn apple is a wide growing flowering plant which has been employed by the local community to treat several ailments in Ethiopia. The purpose of the present work was to assess the antibacterial activity of ethanol, methanol, acetone, chloroform and water extracts of Datura stramonium leaf extracts using broth dilution and agar well diffusion methods against human...
Diversity, knowledge and use of medicinal plants in Abay Chomen District, Horo Guduru Wollega Zone, Oromia Region of Ethiopia
August 2017
An ethnobotanical study of medicinal plants was conducted in Abay Chomen District, Western Ethiopia from September 2014 to August 2015. This study documents indigenous medicinal plant utilization, management and the threats affecting them. Ethnobotanical data were collected using semi structured interviews, field observations, preference and direct matrix ranking with traditional medicine practitioners. The data were...
Stem bark extracts of Endopleura uchi (Huber) Cuatrec: Inhibition of pancreatic lipase and antioxidant activity
August 2017
Pancreatic lipase is considered an important target for the control of hyperlipidemia. Several plants, especially those rich in phenolic metabolites, have been shown to have anti-hyperlipidemic activity and are considered a good alternative for obesity prevention. Extracts of the stem bark of Endopleura uchi (Huber) Cuatrec (Humiriaceae) were evaluated for the inhibitory activity on the pancreatic lipase enzyme, as well...
Traditional Chinese medicine for intestinal adhesion: A meta-analysis of randomized controlled trials
August 2017
For many years, traditional Chinese medicine (TCM) has been used to treat patients with intestinal adhesion. However, no meta-analysis has been previously conducted to investigate the benefits of TCM therapy in patients with such disorder. This paper aims to summarize the beneficial effects of applying TCM as an adjuvant in patients with intestinal adhesion through conducting a meta-analysis. Until October 2016, seven...
Ethnobotanical value of medicinal plant diversity in Cheha district, Guraghe zone, Southern Nations, Nationalities and Peoples (SNNPR) of Ethiopia
July 2017
This study aimed to document information on the use, conservation and threats to medicinal plants in Cheha district, Guraghe Zone, Southern Ethiopia. Thirty informants were randomly selected from four kebeles. Of which, 10 key informants were selected purposively by criteria of age, gender and indigenous knowledge. Ethnobotanical data was collected through semi-structured interview, guided field observation and group...
Chemical constituents isolated from extracts of Annona vepretorum Mart. (Annonaceae) leaves
July 2017
Annona vepretorum Mart. is a medicinal plant endemic to Brazil, popularly known as "araticum", “bruteira” and “pinha da Caatinga”. In this study, the chemical composition of different leaf extracts obtained from this species was evaluated. Chemical compounds were isolated by silica gel column chromatography, resulting in a mixture of steroids (β-sitosterol and stigmasterol) and a...
Antioxidant and free radical scavenging activities of Viola odorata in the search of potential inhibitor of tobacco’s free radicals
July 2017
Tobacco use is a leading cause of cancer morbidity and mortality. Out of several possible components of tobacco, the free radical present in tobacco induces oxidative stress which ultimately leads to the damage of DNA. In the present study, an attempt was made to find the natural potential tobacco free radical scavenger, by using different standard assays. Viola odorata has been known for diverse therapeutic...
Evaluation of essential oils for preventive or curative management of melon gummy stem blight and plant toxicity
July 2017
Melon cultivation is frequently heavily reliant on synthetic fungicides, including products used to control gummy stem blight caused by Stagonosporopsis cucurbitacearum. The essential oils used in controlling plant pathogens may offer an alternative to chemical pesticides. This study evaluated the effectiveness of essential oils to control the gummy stem blight in melon plants. In vitro tests were carried out using...
In-ovo biological activities of Phyllanthus amarus leaf extracts against Newcastle disease virus
July 2017
Newcastle disease virus is a paramyxovirus which causes Newcastle disease in birds. Investigation was done on the effect of leaf extract of Phyllanthus amarus against Newcastle disease virus (NDV) using an in-ovo assay. Nine to eleven day-old viable embryonated chicken eggs (ECE) were used for the assay, these were divided into six groups of six eggs each. Methanol, aqueous and n-hexane extracts of the plant leaves were...
Antibacterial activity of extracts of Stevia rebaudiana Bertoni against Staphylococcus aureus, Staphylococcus epidermidis and Pseudomonas aeruginosa
July 2017
Plants have been an important source of secondary metabolites known for their diverse biological activities; some have been shown to inhibit the development of certain pathogenic microorganisms. Herein, the antimicrobial activity of the carbon tetrachloride, hexane, ethanol, and aqueous extracts of leaves of Stevia rebaudiana Bertoni against Staphylococcus aureus (strain 921), Staphylococcus epidermidis (strains 965,...
Ethnobotanical importance and herbal medicine in Vindhya region of Eastern Uttar Pradesh, India
July 2017
Vindhya region is one of the less studied areas and characterized for rich vegetations of India. The plants species observed in the area have immense potential for the management and treatment of various ailments. The present paper reports to the documentation and conservation of ethnomedicinal plants of Sonebhadra district and their socio- economic relationship with the forest and its resources. The ethnobotanical data...
Malva neglecta: A natural inhibitor of bacterial growth and biofilm formation
June 2017
Malva neglecta, a wild plant that grows in different parts of Lebanon, was noted by residents to have soothing effects if taken during episodes of respiratory tract infections. This study was designed to test for the ability of this plant to inhibit bacterial growth and biofilm formation of clinical bacterial isolates. The results showed that while the aqueous extract of the leaves of the plant did not show any...
Antiproliferative and pro-apoptotic effects of Andean berry juice (Vaccinium meridionale Swartz) on human colon adenocarcinoma SW480 cells
June 2017
Vaccium meridionale Swartz, commonly Andean Berry, has a high content of several phytochemicals, such as anthocyanins, phenolic acids, and other flavonoids. However, in spite of its antioxidant capacity, there is little information about its anticarcinogenic properties. This study evaluated the antiproliferative and pro-apoptotic activity of Andean Berry Juice (ABJ) on human colon adenocarcinoma SW480...
Comparative effect of Nauclea latifolia leaf fractions on blood glucose and lipid profile parameters of alloxan induced-diabetic rats
June 2017
The antidiabetic effects of methanol, N-hexane and ethyl acetate leaf fractions of Nauclea latifolia were investigated in diabetic model rats. 150 and 300mg/kg fractions of N. latifolia were administered orally to the experimental animals at two weeks interval, while their blood glucose levels were taken daily. At the end of the experiment, their lipid profiles were assayed using standard methods. The research data...
Identification of Campsis Flos and its common adulterants using ITS2 sequence of DNA molecular barcoding
June 2017
Internal transcribed spacer 2 (ITS2) is known as a good sequence of DNA molecular barcoding. In this study, the authors authenticated Campsis Flos and its common adulterants based on ITS2 sequence. Campsis Flos has been used in traditional Chinese medicine for many years as a blood activator to promote menstruation. Among its adulterants in the market, the most common are the flowers of Paulownia tomentosa, Hibiscus...
Comparative studies on the possible antioxidant properties of ethanolic seed extracts of Cola nitida (kola nut) and Garcinia kola (bitter kola) on hydrogen peroxide induced oxidative stress in rats
June 2017
Oxidative stress and impaired antioxidant system have been implicated in the pathophysiology of diverse disease states. This research was done to investigate comparatively the possible enzymatic and non-enzymatic antioxidant properties of ethanol extracts of Cola nitida and Garcinia kola in H2O2-challenged rats. Thirty (30) Wistar albino rats were used for this study and were divided into 6 groups of 5 rats per group....
Application of a degreasing process and sequential ultrasound-assisted extraction to obtain phenolic compounds and elucidate of the potential antioxidant of Siparuna guianensis Aublet
June 2017
This study investigated appropriate means to determine the total phenolic content and antioxidant activity of the leaves of Siparuna guianensis. Evaluation by thin layer chromatography (TLC) revealed phenolic compounds in all extracts. The results were confirmed by high-performance liquid chromatography (HPLC), with the identification and quantification of catechin, epigallocatechin gallate and rutin. The methanolic...
Phytochemical and acute toxicity studies of methanolic extracts of selected antimalarial plants of Nupeland, north central Nigeria
May 2017
Malaria remains one of the most prevalent diseases throughout tropics and subtropical areas and its effective chemotherapy remains a problem. Hence the need to continue to explore plants for their therapeutic potentials. In Nupeland, Lannea barteri (monkey’s faru), Piliostigma thonningii (camel’s foot tree or monkey’s bread), Clerodendrum aculeatum (haggar bush or garden quinine) and Crateva adansonii...
Gas chromatography mass spectrometry/Fourier transform infrared (GC-MS/FTIR) spectral analyses of Tithonia diversifolia (Hemsl.) A. Gray leaves
May 2017
Medicinal plants and its products remain the best therapeutic agents for the management of diseases and infections that affect the health of man. Owing to the recorded ethnomedicinal potentials of Tithonia diversifolia (Hemsl.) A. Gray, this study was aimed at investigating the gas chromatography combined with mass spectrometry (GC-MS) and Fourier transform infrared (FT-IR) spectral analyses of methanolic extract of...
Ethnobotanical survey on distribution of medicinal plants in the genus Arisaema in ruins of fortresses used in medieval Japan
May 2017
Members of the genus Arisaema (Araceae) are perennial understory herbs that were traditionally used in medieval Japan in the treatment of flesh wounds resulting from warfare to prevent tetanus. This study aimed to elucidate the distribution of Arisaema in the ruins of fortresses dating from the medieval period in Japan. Two hypotheses were tested: that Arisaema are commonly found in the ruins of fortresses in central...
Biological and antioxidant activity of Gunnera tinctoria (Nalca)
May 2017
The endemic Chilean edible plant Gunnera tinctoria (Nalca) is highly appreciated in the south of Chile by the small farmers. Nevertheless, no background exists about his secondary metabolites. In the present study, in the leaf from G. tinctoria was investigated the content of bioactive compounds like coumaric acid, ascorbic acid and total phenols; the antioxidant capacity was evaluated by...
Optimization of enzyme assisted extraction of polysaccharides from Poria cocos
May 2017
Water-soluble polysaccharide was isolated from Poria cocus by enzyme-assisted method using orthogonal methodology. By single factor test and orthogonal group, the extraction conditions of water-soluble polysaccharide were investigated, such as liquid-solid ratio, temperature, time and pH. The optimum conditions for single factor were as follows Enzyme concentration (%), Extraction temperature oC, Extraction time/h,...
Secondary metabolites from endophytic fungus from Lippia sidoides Cham.
April 2017
Lippia sidoides Cham. (Verbenaceae) is a species native to the Brazilian northeast, widely used in popular medicine. Its leaves were used for the isolation of endophytic fungi and extraction of metabolites. Among them, three were selected according to fungitoxicity tests against the maize phytopathogenic fungus, Curvularia lunata (Wakker). However, the objective of this study was to identify the role of L. sidoides...
Ethnobotanical study of ethnoveterinary plants in Kelem Wollega Zone, Oromia Region, Ethiopia
April 2017
Questionnaire based cross sectional study design was conducted from November 2015 to April 2016 in Dale Sadi district area, Kellem Wollega Zone of Oromia regional state of Ethiopia, to identify potential medicinal plants used for treatment of the livestock ailments. In this study 50 species of medicinal plant species were identified which were categorized under 32 different families. Among the medicinal plants 45(90%)...
HPLC-UV fingerprint profile and bioactivity of Citrus aurantium var. deliciosa fruits: peel and seeds on certain plant-parasitic nematodes
April 2017
A potential approach to valorize citrus peel (P) in addition to seed (S), which remain wastes of the juice abstraction manufacturing, is to custom them as accepted bionematicides. However, information on the limonoids as well aspolyphenolics contents of the peel and seeds of Citrus aurantium var. deliciosa were limited. In the present study, methanolic extracts of the peel and seeds of C. aurantium were analyzed using...
Specialization in ethnomedicinal plant knowledge among herbalists in the forest region of Rivercess County, Liberia
April 2017
The ethnomedicinal uses of plants reported by 22 herbalists in the Rivercess County of Liberia show a rich knowledge of medicinal plant usage for both common and less common health problems. We set out with the objectives of documenting the ethnomedicinal plant knowledge and assessing gender differences in the use of the plants by male and female herbalists. Through semi-structured interviews conducted with herbalists,...
Chemical composition, antiacetylcholinesterase inhibition and toxicity activities of essential oil from Hyptis dilatata (Lamiaceae) flowers
April 2017
The content and chemical composition of the essential oil may vary in certain species according to the climatic period. The aim of this study was to evaluate the influence of seasonality on the chemical composition of the essential oil from Hyptis dilatata flowers, to perform biological activities such as antimicrobial, inhibition of acetylcholinesterase enzyme and to evaluate the toxicity of the essential oil using for...
Antimicrobial activity of Annona crassiflora Mart. against Candida albicans
April 2017
This study evaluated the antimicrobial activity of the ethanol extract of Annona crassiflora Mart., against the fungus, Candida albicans present in the oral microbiota. The tests showed that the fractions of ethanol extract of the root bark and wood root of A. crassiflora showed a positive result. Of the strains studied, three showed sensitivity to 12 fractions and sub-fractions of A. crassiflora (66%). In the strains...
Insecticidal activity of Azadirachta indica A. Juss. extracts on Aleurocanthus woglumi Ashby (Hemiptera: Aleyrodidae)
April 2017
The use of natural products with insecticidal action is a control method compatible with integrated pest management, since it reduces the impacts caused to human health and the environment. This study aimed to assess the effect of Azadirachta indica A. Juss. (Meliaceae) leaf and seed aqueous extracts, on citrus blackfly (Aleurocanthus woglumi Ashby). Citrus x latifolia Tanaka ex Q. Jiménez leaves infested with...
Ethnobotanical study of Arruda quilombo community in the State of Ceará, Brazil
March 2017
The aim of the present study was to investigate the use and storage of medicinal plants in the Arruda quilombo community in the state of Ceará, Brazil. Semi-structured interviews were conducted for the determination of traditional knowledge. The qualitative-quantitative collective subject discourse method was used for the data analysis, focusing the discussion on six categories. The Chi-square test with a 5%...
Anti-inflammatory activity and modulate oxidative stress of Bucida buceras in lipopolysaccharide-stimulated RAW 264.7 macrophages and Carrageenan-induced acute paw edema in rats
March 2017
Since oxidative stress is an important mediator that lead or maintain inflammatory processes, the aim of this work is to evaluate the effects of Bucida buceras on inflammatory response in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and anti-inflammatory effect and redox biomarkers in carrageenan-induced paw edema in rats. B. buceras also known as “black-olive“ belongs to the Combretaceae family and...
Oxidative stabilization of palm olein with isoespintanol (2-isopropyl-3,6-dimethoxy-5-methylphenol) isolated from Oxandra cf xylopioides
March 2017
Antioxidants are used to retard oxidative processes and improve the sensory and nutraceutical quality of cooking oils. Isoespintanol, a monophenol isolated from Oxandra cf. xylopioides, has shown a greater free radical scavenger ability than thymol (biosynthetic analog). Isoespintanol antioxidant capacity was evaluated and compared to butylated hydroxytoluene (BHT). Cytotoxicity, thermal stability and effect on...
Effects of Commiphora swynnertonii on weight and plasma cholesterol levels in Rattus rattus
March 2017
Experimental studies that aimed to determine the effects of crude aqueous resin extracts of the Commiphora swynnertonii on plasma cholesterol levels and weight changes were carried out in rats (Rattus rattus). A total of 24 experimental rats divided into four groups with equal sample size (n=6) were used. Group one (G1) served as negative control that received 0.5ml of distilled water (0 mg/kg) orally. Groups 2 (G2), 3...
Pharmacological potential of Palicourea rigida kunth: A possible participation of flavonoid compounds
March 2017
Palicourea rigida Kunth (Rubiaceae), also called “bate-caixa” or “douradão”, has been used as antihypertensive, antiulcerogenic, anti-inflammatory and analgesic by traditional communities. Pharmacological potential of the ethanol extract from P. rigida (EEPR) and two quercetin derivatives were investigated. Using the high performance liquid chromatography (HPLC) assay, EEPR was analyzed....
In vitro cytotoxic potential of Yacon (Smallanthus sonchifolius) against HT-29, MCF-7 and HDFn cell lines
March 2017
Yacon (Smallanthus sonchifolius) tubers and leaves have been used widely as foodstuff and as remedy for urinary ailments, muscle pain, hyperlipidemia and diabetes mellitus. Recent studies have investigated on isolating active components for their anti-cancer potential against melanoma, cervical cancer and colon cancer. In this study, the cytotoxicity potential of hexane, methanol and DCM extracts of yacon leaves...
Ethnobotanical study of medicinal plants used by agro pastoralist Somali people for the management of human ailments in Jeldesa Cluster, Dire Dawa Administration, Eastern Ethiopia
March 2017
Ethnobotanical study of medicinal plants in selected kebeles of Jeldesa cluster, Dire Dawa Administration, eastern Ethiopia was carried out with the aim of assessing and documenting the indigenous knowledge of medicinal plants used in the communities and preserves it to be used by the next generations. Ethnobotanical data collection was carried out from September 2015 to March 2016. Three study sites (kebeles) were...
Volatile constituents of Distichochlamys citrea M. F. Newman and Distichochlamys orlowii K. Larsen & M. F. Newman (Zingiberaceae) from Vietnam
March 2017
The characterization of chemical constituents of hydrodistilled essential oils from the rhizomes of Distichochlamys citrea M.F. Newman and Distichochlamys orlowii Larsen & M.F. Newman collected from Pù Mát National Park, Nghệ An Province, Vietnam, was performed by means of gas chromatography-flame ionization detector (GC-FID) and gas chromatography-mass spectrometry (GC-MS) techniques. The main...
Medicinal plants and herbalist preferences around Bwindi Impenetrable National Park
February 2017
Many people in Uganda, particularly in the rural areas depend on herbal medicine for health care. Although, medicinal plants are collected from different habitats, most of them are collected from the wild. Claims indicate that men use more forest products than women; and that women prefer younger vegetation succession stages as compared to those preferred by men for harvesting medicinal plants. However, there was no...
Effects of lemon balm (Melissa officinalis) on behavioral deficits and memory impairment of rats surviving sepsis
February 2017
Sepsis has become one of the most frequent causes of mortality in intensive care centres. So far, there is no effective pharmacotherapy that can prevent or improve the neurological consequences and enhance survival. The goal of this study is to investigate the neuroprotective effect of lemon balm (Melissa officinalis) on behavioural dysfunctions produced in sepsis-surviving rats. Adult male rats were subjected to caecal...
Mangiferin content, carotenoids, tannins and oxygen radical absorbance capacity (ORAC) values of six mango (Mangifera indica) cultivars from the Colombian Caribbean
February 2017
Mango is one of the tropical fruits of greater production and consumption in the world, and a rich source of bioactive compounds, with various functional properties such as antioxidant activity. In Colombia, mango’s market is very broad and diverse. However, there are very few studies that determined the content of bioactive secondary metabolites. The objective of this study was to evaluated the content of...
Anthelmintic activity of Artemisia annua in sheep-model
February 2017
Artemisia annua L. is a well-known source of artemisinin, an antimalarial drug. This compound has been used in traditional medicine to treat malaria for many years. The anthelmintic property of A. annua has also been attributed to artemisinin, hence the belief that artemisinin could be useful as an alternative anthelmintic to control Haemonchus contortus in livestock. The present study focused on evaluating the...
Protective effect of eucalyptus oil on pulmonary destruction and inflammation in chronic obstructive pulmonary disease (COPD) in rats
February 2017
Eucalyptus oil (EO), an essential oil isolated from Eucalyptus leaves, was examined for its effect on lipopolysaccharide (LPS) and Klebsiella pneumoniae-induced COPD in rats. The COPD model was induced by instilling intratracheally with LPS and K. pneumoniae. The test compound, EO (30, 100 and 300 mg/kg), prednisone acetate (10 mg/kg) or vehicle was instilled intragastrically after three weeks exposure to LPS and K....
Response of Rheum australe L. (rhubarb), (Polygonaceae) an endangered medicinal plant species of Kashmir Himalaya, to organic-inorganic fertilization and its impact on the active component Rhein
February 2017
Many medicinal plant species, including Rheum australe L. (rhubarb), are being exploited from the wild source at an alarming rate. This has resulted in the loss of biodiversity of the species. Roots of R. australe have been used in traditional medicine for years for treating various kinds of diseases. The species has been ruthlessly harvested from the wild source and has become endangered. Consequently, preventing the...
Effect of the extract of Hypericum perforatum on neurodevelopment of regions related to pain control and convulsion
February 2017
Hypericum perforatum (HP) is well-known by the population of the world as herb with antidepressant effect. Its various components, such as hypericin and hyperforin, provide many other effects for this plant, for example, antinociceptive and anticonvulsant. The aim of this work was to determine whether HP administration during pregnancy can cause changes in neurodevelopment related to pain control and seizures in rats...
Laxative properties of aqueous and methanolic extracts of mature stem bark of Neoboutonia velutina Prain (Euphorbiaceae) in rats
February 2017
Neoboutonia velutina. Prain is a plant used in Cameroonian ethnomedicine for the treatment of digestive disorders such as constipation. This study was conducted to evaluate the laxative properties of aqueous and methanolic extracts of N. velutina in rats. The laxative properties as mentioned by the consulted traditional healer were firstly determined, through an evaluation of fecal emission outset, number of wet...
Bioactive rich extracts from Terminalia ferdinandiana by enzyme-assisted extraction: A simple food safe extraction method
February 2017
A food grade compatible enzyme assisted extraction (EAE) technique for extracting bioactive compounds from freeze-dried Kakadu plum puree was evaluated. To optimise the extraction, a central composite rotatable design (CCRD) was conducted and effects of solvent concentration, enzyme concentration and time of reaction on extracted levels of free ellagic acid (fEA), ascorbic acid (AA) and total phenolic content (TPC) were...
New insights of Nettle (Urtica urens): Antioxidant and antimicrobial activities
January 2017
Urtica urens is classified into the sub family of Rosales, belonging to the Urticaceae family. Their well-established beneficial properties to human health were mainly related to their phenolic content. Nettle extracts showed that an antioxidant and antimicrobial potentials. Among the different nettle extracts methanol extract (EMO) has the highest phenolic content (86.5±1.36 mg EGA/g DM) and lowest value was...
In vitro studies of larvicidal effects of some plant extracts against Anopheles gambiae larvae (Diptera: Culicidae)
January 2017
Larvicidal effects of plant extracts against larvae of Anopheles gambiae were studied in the malaria entomology laboratory at Mendefera. The aim of the study was to evaluate ethanol and hot water extracts from leaves of seven different plants, viz., Azadirachta indica, Eucalyptus globulus, Tagetes minuta, Datura stramonium, Lantana camara, Ricinus communis and Jatropha curcas, as natural larvicides against third instar...
Hypoglycaemic effect of fractions and crude methanolic leaf extract of Phyllanthus fraternus in streptozotocin - induced diabetic and normal rats
January 2017
Treatments of diabetes with available agents come with one or more side effects, hence, the need for continual search of alternative treatment agents from medicinal plants. This study was designed to analyse qualitatively and quantitatively some phytochemicals in methanolic extract in Phyllanthus fraternus and evaluate their hypoglycaemic activity in both diabetic and normal rats. Sixty-six rats were used of which...
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