African Journal of
Agricultural Research

  • Abbreviation: Afr. J. Agric. Res.
  • Language: English
  • ISSN: 1991-637X
  • DOI: 10.5897/AJAR
  • Start Year: 2006
  • Published Articles: 6688

Full Length Research Paper

Effect of in ovo injection of cadmium on chicken embryo heart

Krzysztof Pawlak1*, MaÅ‚gorzta Dżugan2, Dorota Wojtysiak3, Marcin Lis1 and Jerzy NiedzióÅ‚ka1
1Department of Poultry and Fur Animal Breeding and Animal Hygiene, University of Agriculture in Krakow, Aleja Adama Mickiewicza 21, Kraków, Poland. 2Department of Food Chemistry and Toxicology, University of Rzeszów, Aleja Tadeusza Rejtana 16, Rzeszów, Poland. 3Department of Animal Reproduction and Anatomy, University of Agriculture in Kraków, Aleja Adama Mickiewicza 21, Kraków, Poland.
Email: [email protected]

  •  Accepted: 26 March 2013
  •  Published: 02 May 2013


Due to the ease of absorption, accumulation in tissues, and extremely long biological half-life in the body, cadmium is considered one of the most hazardous heavy metals. The aim of the study was to investigate the effect of in ovo injection of cadmium on chicken embryo heart. A total of 160 chicken hatching eggs were used in the study. On day 4 of incubation, eggs from the experimental groups were injected with cadmium at a dose of 1 and 5 µg/egg and the incubation was prolonged to 21 day until hatching. Cadmium was found to slow the heart rate and reduce heart weight. In embryos exposed to 5 µg of cadmium, the histological analysis and aminotransferases concentration confirmed the occurrence of inflammatory processes in the heart muscle.


Key words: Cadmium, heart, chicken embryo, cardiotoxicity.