African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12496

Full Length Research Paper

Evaluation of the anti-fertility activity of stem bark of Crataeva nurvala buch-hum

Bhaskar, V. H.1*, Profulla, Kumar M.2, Balakrishnan, B. R.2 Balakrishnan, N.3and Sangameswaran, B.2
  1M.P. Patel College of Pharmacy, Kapadwanji, Gujarat - 387 620, India. 2Medicinal Plant Research Centre, Vinayaka Mission’s College of Pharmacy. Vinayaka Missions University, Salem 636 008, Tamil Nadu, India. 3Technocrats Institute of Technology - Pharmacy, Bhopal- 462 021(M.P), India.
Email: [email protected]

  •  Accepted: 22 May 2009
  •  Published: 16 November 2009

Abstract

 

The ethanol and aqueous extracts of the dried stem bark of the plant Crataeva nurvala Buch-Hum (Capparidaceae) have been found to possess significant anti-fertility effects in rats. Both ethanol and aqueous extracts exhibited partial and complete resorption of implants at 300 and 600 mg/kg b.wt dose levels, respectively. In estrogenic activity study, both the extracts increased uterine weight and caused opening and cornification of vagina in immature rats. The present work justifies its effectiveness in preventing pregnancy in all rats at dose levels.

 

Key words: Anti-fertility, anti-implantation, aqueous and ethanol extracts, Crataeva nurvala.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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