African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12500

Full Length Research Paper

In vitro study of antiamoebic activity of methanol extract of fruit of Pimpinella anisum on trophozoites of Entamoeba histolytica HM1-IMSS

  Quiñones-Gutiérrez Y.*, Verde-Star M. J., Rivas-Morales C., Oranday-Cárdenas A., Mercado-Hernández R., Chávez-Montes A. and Barrón-González M. P.      
  School of Biological Sciences, UANL Ciudad Universitaria, AP 46-F, CP 66451, San Nicolas de los Garza, N. L., Mexico.  
Email: [email protected]

  •  Accepted: 02 November 2012
  •  Published: 17 April 2013

Abstract

 

The aniseed plant Pimpinella anisum (Saunf-Hindi) is one of the most ancient medicinal plants used by man. Currently, this plant has several uses in the food industry as spice, whereas in the pharmacopoeia, it is used as an expectorant in digestive disturbances, as mild diuretic, and as insect repellent in external use. In this paper, we evaluated the biological activity of methanolic extract of P. anisum on in vitro growth of Entamoeba histolytica HM1-IMSS under axenic conditions. We observed that the growth inhibition of E. histolytica was at CI50 = 0.034 µg/mL. Results confirm the antiamoebic activity of the methanolic extract of P. anisum.

 

Key words: Pimpinella anisumEntamoeba histolytica, antiamoebic activity, medicinal plants.