African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12502

Full Length Research Paper

Saikosaponins a and d roots concentration in five Bupleurum species from four mountains in China

  L. Nyobe*, J-T. Zhang and S.T. Huang  
College of Life Sciences, Beijing Normal University – Beijing 100875 P.R. China.
Email: [email protected]

  •  Accepted: 02 December 2011
  •  Published: 16 January 2012

Abstract

 

Bupleurum species are widely distributed in China and its diversity is of a potential commercial incomes. In this study, five species of the genus Bupleurum were collected in four mountains in North China areas. The saikosaponins a and d (SSa and SSd) roots concentration were determined by high performance liquid chromatography (HPLC) and the results revealed that B. smithii, B. sibiricum and B. scorzonerifolium might be of great interest because of their high SSd content in which the –OH of C-23 is involved in their bioactivity. This study, besides being helpful for medicine quality control, provides an insight of the importance saikosaponins. Especially, SSd might play in the discovery of new drugs against bacterial or viral diseases such as HIV.

 

Key words:  Bupleurum spp., Saikosaponins a and d, roots content determination, HPLC.

Copyright © 2025 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 11 No. 5
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES