The search for more safe and nutritive natural sweeteners as an alternative to commercial sweeteners, which are implicated in obesity and diabetes mellitus has led to the utilization of the African locust bean (Parkia biglobosa) pulp which is rich in dietary fibres, soluble sugars and vitamins. Mango peels contain antioxidants, fiber and a source of Nutraceuticals. The mixture of the pulp and mango peel were blended and used to determined Incremental Area Under Curve of the natural sweetener compared to synthetic sweeteners. Aqueous extraction was done on the viable blend which had a low glycaemic index and administered to alloxan induced wistar rats along with characterization of soluble sugars. The natural sweetener enhanced the reduction of Low Density Lipoprotein (LDL) while the commercial sweetener revealed a high concentration of LDL in the serum of rat (P> 0.05). Exposure of serum to saccharine increased the levels of Superoxide Dismutase (SOD) in the rats which was significantly(P>0.05) different compared to the natural sweetener. The cummulative repression of LDL and SOD levels and serum glucose level of 6.72mMol/L provides data to support optimal valorization of an African locust beans pulp- mango peel blend as an alternative sweetener for management of diabetes mellitus.

Keywords: Nutraceuticals., Density Lipoprotein .African locust beans