African Journal of
Biochemistry Research

  • Abbreviation: Afr. J. Biochem. Res.
  • Language: English
  • ISSN: 1996-0778
  • DOI: 10.5897/AJBR
  • Start Year: 2007
  • Published Articles: 425

Article in Press

Insecticides Resistance in Anopheles Mosquitoes from Katsina State Nigeria

Nura Lawal, Imam Nasir Usman, Mukhtar Aliyu, Abdullahi Abdulkadir Imam

  •  Received: 18 May 2023
  •  Accepted: 06 October 2023
It has been previously reported that insecticide resistance among the vectors of malaria and lymphatic filariasis (LF) exist in the African continent which could unintentionally affect different species of Anopheles mosquitoes found in Katsina State Nigeria and its insecticides resistance. This study's objectives were to identify the Anopheles mosquito species that can be found in Katsina State Nigeria and its profile insecticide resistance. The study was carried out in Gajerar Giwa village and Batagarawa town. Using a mechanical aspirator, blood-feeding mosquitoes were captured indoors and identified morphologically and molecularly. The WHO procedure was followed in insecticide susceptibility bioassay using F1 mosquitoes, and PCR was used to check for the existence of the kdr mutation in Anopheles mosquitoes that had survived exposure to permethrin. They were identified as Anopheles gambiae s.s., Anopheles coluzzi, and Anopheles funestus s.s. An insecticide susceptibility test revealed that Anopheles gambiae s.l from Batagarawa town and Anopheles funestus s.l from Gajerar Giwa hamlet were more susceptible to deltamethrin, bendiocarb, propoxur, and malathion but less resistant to permethrin and DDT. Anopheles funestus s.l from the village of Gajerar Giwa showed a death rate increase from 44.2 to 62.44% after pre-exposure to 4% piperonyl butoxide (PBO), which was treated with permethrin. The execution of an effective vector control strategy can be guided by the presence of permethrin and DDT crosses resistance in both Anopheles gambiae s.l and Anopheles funestus s.l.

Keywords: Permethrin, malathion, propoxur and bendiocarb.