April 2015

Detection of DNA damage in lead (Pb) exposed city traffic wardens in Pakistan

Lead (Pb) is one of the toxic metals and is commonly used in industries. It affects multiple systems and has role in the production of reactive oxygen species (ROS). The objective of the present study was to determine Pb levels and to detect DNA damage in traffic wardens of Lahore, Pakistan. A total of 90 subjects were selected including 60 traffic wardens working in field and 30 working in administrative zones. The...

Author(s): Ayesha Pervez, Fozan Ahmed, Nazish Mehmood Aisha, Salman Idrees, Muhammad Ikram Ullah, Mohammad Zamir Ahmad, Aftab Ahmed and Muhammad Jawad Hassan

April 2015

Biochemical changes in blood and tissues of Wistar rats following administration of anti-tuberculosis drugs

Tuberculosis (TB) remains a major public health problem worldwide especially in resource-limited countries of Africa and Asia. The disease is curable with drugs but information on biochemical changes and oxidative indices due to anti-TB drugs is not readily available. This study was designed to investigate in vivo effects of anti-TB drugs in male Wistar rats. Fourteen adult male rats were randomly divided into two...

Author(s): Aderemi Oludiran Kehinde, and Oluwatosin Adaramoye