July 2020

Evaluation of the effects of Azadirachta indica leaf on haematology, lipid profile, body weight and organ-system functions of streptozotocin-induced diabetic male rats

This study was carried out to evaluate the effects of ethanol extract of Azadirachta indica leaf on haematological parameters, lipid profile, body weight, organ weight and histopathological functions of streptozotocin-induced diabetic rats. Diabetes was induced by a single intraperitoneal administration of streptozotocin (50 mg/kg bw.). The haematological parameters, lipid profile and histopathological investigations...

Author(s): Ezeigwe Obiajulu Christian, Okani Chukwudi Onyeaghana, Nnadi Naomi Ngozi, Obiukwu Onyinye Olivia, Ekwunoh Peter Okwukwe, Obayuwana Erhunmwense Ann, Okibedi Frances Uchenna and Obi Chioma Henrietta  

July 2020

Inhibitory potential and antidiabetic activity of leaf extracts of Vitex doniana

Pancreatic alpha (α)-amylase and intestinal α-glucosidase involved in the enzymatic breakdown of dietary carbohydrates are implicated in postprandial hyperglycemia. The inhibition of these two enzymes has been exploited in the design of antidiabetic drugs. This study was therefore designed to investigate the ability of the leaf extracts of Vitex doniana to inhibit α-amylase and α-glucosidase as...

Author(s): Ani Onuabuchi Nnenna, Udedi Stanley Chidi, Anajekwu Benedette Azuka, Asogwa Kingsley Kelechi and Ekwealor Kenneth Udeh  

July 2020

Antibacterial activity of endophytic fungi isolated from leaves of medicinal Plant Leucas martinicensis L. growing in a Kenyan tropical forest

Infectious diseases are major threat to public health; a problem that has been exacerbated by emergence of multi-drug resistant (MDR) strains. Finding alternative antimicrobial compounds from natural sources such as fungal endophytes and medicinal plants is crucial for addressing antimicrobial resistance. Thus, in this study search for endophytes with antibacterial activities from leaves of medicinal plant Leucas...

Author(s): Ruth Moraa Obare, Stephen A. Indieka and Josphat Matasyoh  

July 2020

Study of the nutritional values and sanitary quality of soumbala collected from six regions of Burkina Faso

Soumbala is regularly consumed as a condiment in most households in Burkina Faso. The purpose of this study was, therefore, to assess its nutritional and sanitary quality. To achieve this purpose, samples of sombala have been analysed for the determination of pH, water and ash contents, biochemical parameters, mineral elements, and aflatoxin contents. Results showed that Fada N’Gourma soumbala had the highest...

Author(s): Elie Kabré, Raoul Bazié, Moumouni Bandé, Thierry Sanou, Fulbert Nikiéma and Jean Sakandé,