July 2019

Statistical optimization of L–glutaminase production by Trichoderma species under solid state fermentation using African locust beans as substrate

Six strains of Trichoderma species isolated from soil and air samples were screened for extracellular L-glutaminase production. The highest enzyme producing isolate, Trichoderma longibrachiatum was subjected to screening and nutrients optimization experiments under solid state fermentation using a constant weight of African locust beans as substrate. A specific activity of 54.96 U/mg was achieved at 1% (w/v) glutamine,...

Author(s): Musa Olatunji Olarewaju and Humphrey Chukwuemeka Nzelibe  

July 2019

The pro-oxidant effect of dextran sodium sulphate on oxidative stress biomarkers and antioxidant enzymes in Drososphila melanogaster

This study sought to evaluate the behavioural and biochemical effects of Dextran Sodium Sulphate (DSS) on the oxidative stress biomarkers and antioxidant enzymes. Drosophila melanogaster (both sexes) of 3 days old were exposed to various DSS incorporated diets at concentrations, 0.5 - 3.0% for a period of 14 days (Survival rate). The second phase comprised of 3 groups; Group I- Control (normal diet), Group II-0.5% DSS,...

Author(s): Augustina O. Akinsanmi, Opeyemi Balogun, Johnson O. Titlayo, Ishaya Y. Longdet and Aguiyi C. John,