African Journal of
Medical and Health Sciences

OFFICIAL PUBLICATION OF THE FEDERAL TEACHING HOSPITAL, ABAKALIKI, NIGERIA
  • Abbreviation: Afr. J. Med. Health Sci.
  • Language: English
  • ISSN: 2384-5589
  • DOI: 10.5897/AJMHS
  • Start Year: 2017
  • Published Articles: 78

Full Length Research Paper

Seroprevalence of toxoplasmosis in reproductive-aged women in Jeddah Province, Saudi Arabia: A retrospective study

Raafat Abdel Moneim Hassanein
  • Raafat Abdel Moneim Hassanein
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
  • Google Scholar
Adel Galal El-Shemi
  • Adel Galal El-Shemi
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
  • Google Scholar
Ameer Ahmed Alahmadi
  • Ameer Ahmed Alahmadi
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
  • Google Scholar
Waslallah Saad Almatery
  • Waslallah Saad Almatery
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
  • Google Scholar
Mohammed Othman Alkurbi
  • Mohammed Othman Alkurbi
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
  • Google Scholar
Radi Taha Alsafi
  • Radi Taha Alsafi
  • Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia.
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  •  Received: 21 November 2021
  •  Accepted: 04 March 2022
  •  Published: 31 December 2022

Abstract

Toxoplasmosis; an opportunistic protozoan parasitic disease caused by Toxoplasma gondii, still imposes a major health concern and a significant economic burden worldwide particularly in developing countries. Nevertheless, the epidemiological status of toxoplasmosis among Saudi female population remains largely unknown. Therefore, the present hospital-based retrospective study aimed to determine the seroprevalence of T. gondii infection among reproductive-aged Saudi women residing in Jeddah region of Saudi Arabia. The study was conducted at three governmental hospitals in Jeddah region of Saudi Arabia; King Fahad, King Abdulaziz and East Jeddah hospitals, from January 2019 and March 2021, and included 2431 reproductive-aged Saudi women (15-49 years old) who were screened by enzyme linked immunosorbent assay (ELISA) for the seroprevalence of anti-T. gondii IgG and IgM antibodies. Among the 2431 studied women, 378 (15.5%) were seropositive for anti-T. gondii IgG antibodies, while 43 (1.8%) were seropositive for anti-T. gondii IgM, and 13 (0.53) were seropositive for both anti-T. gondii IgG and IgM antibodies. Moreover, the highest proportion of seropositive for anti-T. gondii IgG antibodies (4.77%) was detected in 30-34 years old women, while the highest proportion of seropositive for anti-T. gondii IgM antibodies (0.69%) was in women with age of  25 to 29 years, and the highest proportion of co-seropositive for both anti-T. gondii IgG and IgM antibodies (0.21%) was in the 25-29 years old women. Taken together, the present findings identified the seroprevalence situation of toxoplasmosis among reproductive-aged women in some Saudi communities and raise the importance to increase the screening programs and implements to control toxoplasmosis in Saudi Arabia.

Key words: Toxoplasma gondii, Seroprevalence, reproductive-aged Saudi women.