African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Short Communication

Laboratory analysis of a fatal meningococcal case due to serogroup B Neisseria meningitidis belonging to ST- 4821 complex

Zengguo Wang*, Tiejun Hou, Zhijun Chen, Jinsong Li, Shouzhi Wu, Xiaoguang Wei, Yahui Sun and Quanli Du
Xi’an Center for Disease Control and Prevention, 599 Xi Ying Road, Xi’an, 710054, P. R. China.
Email: [email protected]

  •  Accepted: 12 November 2009
  •  Published: 18 August 2011


We describle a suspicious Meningococcal death case, confirmating by the laboratory PCR methods. The infection developed rapidly within only 24 h until the patient died. Analyzing the close contact strain and the DNA template extracted from the serum of this patient, we characterized a serogroup B Neisseria meningitidis as the pathogen of this case, which, in terms of sequence typing, belonged to ST-4821 complex which first characterized in serogroup C Neisseria meningitidis as a new unique hypervirulent meningococcal lineages.


Key words: Neisseria meningitidis, multilocus sequence typing, serogroup.