The prevalence of Rotavirus (RV)-related gastroenteritis in Cameroon was monitored in this study, identifying the circulating G-P types, and the presence of co-infection with intestinal parasites. The stool samples were examined for rotaviruses using chromatographic and molecular techniques, and parasites were identified by macroscopic and microscopic examination. 38% of samples were RV positive. Data revealed the presence of three different G-genotypes (G1, G2 and G8) and three P-genotypes (P , P and P). The main G-P combination was G1+G2P. Entamoeba histolytica was identified in 44.4% of stool samples. The G2P genotype identified is an unusual strain with the G1P or G2P more common. Genotype G8 strains, also associated with animals, have been sporadically recovered from humans and have been considered for inclusion in bovine-human reassortant vaccine. Epidemiological RV strain surveillance should be continued in order to support RV vaccination campaigns. The results also show a high prevalence of intestinal parasite infections.
Key words: Gastroenteritis, rotavirus, G/P genotype, semi-nested multiplex PCR, intestinal parasites, Cameroon.
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