Full Length Research Paper
Abstract
Avibacterium paragallinarum causes a highly contagious disease in chickens called infectious coryza. We have previously isolated A. paragallinarum from diseased chickens and demonstrated their virulence in experimental infection in different poultry species. In the present study, the isolates were screened for selected resistance genes for clinically relevant antibiotics. The study demonstrated resistance genes for sulphamethoxazole, tetracycline, streptomycin and ampicillin resistance in the isolates. Multiple resistance and resistance genes to streptomycin (strA), ampicillin (blaTEM), tetracycline (tetC and tetA) and sulphamethoxazole (sul2) in isolates of A. paragallinarum are reported. The demonstration of these genes in A. paragallinarum, similar to what has been demonstrated in other respiratory pathogens, is a concern for potential horizontal spread of multiple drug resistance leading to treatment failures in different respiratory diseases.
Key words: Antibiotic resistance genes, Avibacterium paragallinarum.
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