Full Length Research Paper
Abstract
To explore interleukin-32 relationship with tuberculosis, we detected interleukin-32 expression level in the serum samples of patients with active tuberculosis. Forty (40) TB patients (16 males and 24 females) from Third People's Hospital of Kunming, China, and 17 healthy controls (10 males and 7 females) from the Center for Disease Control and Prevention of Kunming, China, were selected. An enzyme-linked immunosorbent assay (ELISA) was used to quantify IL-32 levels. IL-32 levels of TB group were significantly higher than the control group (p<0.001). These data show that IL-32 plays an important role in immune responses to human infection with Mycobacterium tuberculosis.
Key words: Interleukin-32, Mycobacterium tuberculosis, tuberculosis, enzyme-linked immunosorbent assay.
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