African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5211

Full Length Research Paper

Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria

Z. Suhaili1*, C. C. Yeo1, H. N. Yasin1, N. A. Badaludin1 and Z. A. Zakaria2
  1Faculty of Agriculture and Biotechnology, University Sultan Zainal Abidin, Kampus Kota, Jalan Sultan Mahmud, 20400 Kuala Terengganu, Malaysia. 2Department of Biomedical Sciences, Faculty of Medicine and Health Science, University Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.
Email: [email protected]

  •  Accepted: 23 August 2011
  •  Published: 09 December 2011



Jatropha curcas is a drought-resistant tree belonging to the family Euphorbiaceae. The latex of J. curcas has been traditionally used to heal wounds and has reported anti-coagulant and coagulant properties. In this study, fractions of the methanol, aqueous, ethyl acetate and hexane extracts from the Jatropha latex were tested for antibacterial properties against nine different human pathogenic bacteria, namely three different isolates of Staphylococcus aureus (one methicillin-resistant strain MRSA ATCC 33591, and two methicillin-sensitive strains MSSA ATCC 29213 and ATCC 25174), Salmonella enterica serovar typhiStreptococcus agalactiaeSerratia marcescensKlebsiella pneumoniaeEnterococcus faecalis (E248), Escherichia coli (ATCC 35218), Listeria monocytogenes (IMR L10), and Morganella morgenii (IMR MM99). The zones of inhibition produced by the extracts using an agar well diffusion method against the test microorganisms were found to range from 2.7 to 29 mm. The methanol extract was found to be the most effective extract with MIC values ranging from 0.39 mg/ml for methicillin-sensitive S. aureus and 6.25 mg/ml for S. marcescens. Hexane extracts did not show any antibacterial activity. Phytochemical screening of the J. curcas latex indicated the presence of saponins and tannins which are known to have antibacterial properties.


Key words: Jatropha curcas latex, antibacterial properties and human pathogenic bacteria.