African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5211

Full Length Research Paper

Clinical features, epidemiology and outcomes of infective endocarditis at a general hospital in China: A 10-year survey

Yun Cai, Dong Chai* and Rui Wang
Department of Clinical Pharmacology, the People's Liberation Army (PLA) General Hospital, Beijing 100853, People’s Republic of China.
Email: [email protected]

  •  Accepted: 24 October 2011
  •  Published: 09 December 2011



This study retrospectively investigated the epidemiology, treatment and outcome of infective endocarditis (IE) in People's Liberation Army (PLA) General Hospital from 1997-2007. Totally, 65 cases were included. The results showed that bacteria were isolated from 63.08% of the IE cases. Staphylococcus was the main pathogen causing IE (43.9%), followed by Streptococcus (41.5%). Surgical treatment was performed for 81.5% (53/65) of the IE patients. The most common surgery was aortic valve replacement conducted for 58.18% of the IE patients. Six patients (9.23%) died during hospitalization. Antimicrobial agents including penicillin, vancomycin and quinolones were most frequently utilized. We concluded that early diagnosis, timely surgery and appropriate utilization of antibiotics can improve the prognosis of IE patients.


Key words: Infective endocarditis (IE), clinical features, epidemiology.