African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5211

Full Length Research Paper

In vitro evaluation of anti-staphylococcal activity of Ganoderma lucidum, Ganoderma praelongum and Ganoderma resinaceum from Pune, India

  Abdulghani Ameri1*, Jitendra G. Vaidya2 and Subhash S. Deokule3    
1Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahwaz, Iran.2Department of Botany, University of Pune, Pune-411007, India.
Email: [email protected]

  •  Accepted: 25 January 2011
  •  Published: 04 February 2011



Antimicrobial activity of Ganoderma praelongum, Ganoderma resinaceum andGanoderma lucidum were evaluated against thirty strains of clinical isolates of methicillin resistant and methicillin sensitive Staphylococcus aureus (MSSA) by the well agar diffusion and microtiter plate dilution. Chloroform, ethyl acetate, methanol, and water were used as extractive solvents. Standard antibiotic disks of methicillin, vancomycin, linezolid, and mupirocin were used for susceptibility testing of the test microorganisms. Maximum activity of crude extracts was exhibited by ethyl acetate. Sesquiterpeoids extract of G. praelongum (35.67 ± 0.62 mm) and minimum inhibitory concentration (MIC) of 0.390 – 6.25 mg/ml. Diterpenoids and triterpenoids displayed moderate activity while polysaccharides IIIa and IIIb showed weak activity. All bacterial strains were resistant to polysaccharides I and II.


Key words: Ganoderma praelongum, Ganoderma resinaceum, Ganoderma lucidum,Staphylococcus aureus, antimicrobial activity.