African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

In vitro antibacterial and antifungal effect of some medicinal plants

  Batool Sadeghi-Nejad1* and Maryam Azish2
  1Department of Medical Mycology, Cellular and Molecular Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran. 2Department of Medical Mycology, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
Email: [email protected]

  •  Accepted: 21 February 2013
  •  Published: 19 July 2013



The aim of this study was to evaluate the antimicrobial activity of five species of plants known as medicinal plants and used commonly in folkloric medicine. They are: Nigella sativaFoeniculum vulgareBlack piper, Loranthus capitellatusCassia alata and Drynariaqurshiforia. In this study, we investigated the antibacterial and antifungal effects of these plants on Gram- positive and negative bacterial isolates, such as Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella sp. and fungi isolates, such asCandida albicansCandida tropicalisCandida glabrata; Aspergillus nigerAspergillus flavusAspergillus terrusAlternaria sp., Trichophyton mentagrophytes and Microsporum gypseum. The antimicrobial activity of the plants extracts against isolated pathogenic bacteria and fungi was assayed by well-diffusion method for bacteria and Candida and pure plate method for dermatophytes. The minimum inhibitory concentrations (MIC) for bacteria and fungi were 0.625 to 40 mg ml-1 and 2.5 to 40 mg ml-1, respectively. The plant extracts were revealed to be effective in inhibiting the growth of tested bacteria and fungi.


Key words: Antibacterial, antifungal activity, medicinal plants.