African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5210

Full Length Research Paper

Trends and characteristics of patients admitted with musculoskeletal tuberculosis to a referral hospital from 2003 to 2008

C. H. Iredia1, O. O. Oguntibeju2*, H. A. Lewis1 and K. Mokwena1
  1School of Public Health, MEDUNSA, University of Limpopo, Pretoria, South Africa. 2Department of Biomedical Sciences, Faculty of Health and Health Sciences, Cape Peninsula University of Technology, Bellville, South Africa.
Email: [email protected], [email protected]

  •  Accepted: 08 December 2010
  •  Published: 04 March 2011



Tuberculosis (TB) remains the most common cause of death from infectious disease world-wide. Extrapulmonary diagnosis remains challenging especially in developing countries such as Botswana. The increasing global burden of tuberculosis is linked to HIV-infection and sub-Saharan Africa is the hardest hit by tuberculosis epidemics due to the high incidence and prevalence of HIV-infection. This study evaluated the prevalence and trends of musculoskeletal tuberculosis in Nyangabgwe Referral Hospital in the Northern part of Botswana. A descriptive retrospective study was performed whereby all patients admitted with musculoskeletal TB to the Nyangabgwe Referral Hospital, Botswana between 1st January, 2003 and the 31st December, 2008 were reviewed. A total of 744 TB cases were reported between 2003 and 2008. A review of the reports showed that 53 cases were diagnosed with mTB. Seventy-seven percent of the patient files reviewed showed a decline in the prevalence of mTB cases from 10.3% in 2003 to 3.9% in 2008. Prevalence of HIV-infection among the TB cases was 39%, and 81% of these had CD4+T-cell counts of less than 200cells/ul. This decline in mTB prevalence may be related to an increased provision of isoniazid preventive therapy (IPT) and highly active antiretroviral therapy (HAART) in Botswana over the past 5 years.


Key words: Musculoskeletal tuberculosis, patients, Africa, prevalence, human immunodeficiency virus (HIV), Botswana.