African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Short Communication

Helicobacter pylori and eye diseases in an Iranian hospital

  Gholamhossein Yaghoobi1, Mohammad Reza Rezvani1* and Elahe Heidari2
  1Birjand  University of Medical sciences, Ophthalmology Department, Valiasr Hospital, Southern Khorasan, Social Determinant Health Research center, Birjand, Iran. 2Mashad University of Medical Science, Pediatrics ward, Emmam Reza Hospital, Mashad, Iran.
Email: [email protected]

  •  Accepted: 26 April 2013
  •  Published: 20 September 2013



There is evidence of Helicobacter pylori infection that induces eye diseases. This study was done to find if there is any association between H. Pylori and ocular diseases, and if there is any difference in color of eye among them. Of all the 35 patients tested for biopsy with positive H. pylori, 23 (65.7%) were females and 12 (34.3%), males. The mean age of patients was 39.65±18.55 years. 20 (57.1%) patients were below 40 years old; 8 (22.9%) patients, 40 to 60 years and only 7 patients were more than 60 years old. Most of the patients were 20 years old and had no ophthalmic or systemic diseases in juvenile age group; most of them with the best correct vision were within normal measure, except the old patients who had normal tension glaucoma and two cataract cases. Brown eyes were the commonest but blue color was the least without any risk of ocular diseases or H. Pylori associated with more prevalent brown iris color in study group. Ophthalmic extragastric diseases do not show any association between eye diseases and H. pyloriinfection in juvenile age groups. Pesudoexfolitive glaucoma and two cases of cataract were among the old age related diseases which may be due to the late appearance of H. pylori effect. Best visual acuity, cup/disc character and brown color were the most associated finding.


Key words: Helicobacter pylori, extragastric manifestations, ophthalmic diseases.