African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5236

Full Length Research Paper

Role of probiotics in prevention of hospital acquired pneumonia in Egyptian children admitted to Pediatric Intensive Care Unit of Mansoura University Children’s Hospital

Niveen El-Wakeel*
  • Niveen El-Wakeel*
  • Medical Microbiology and Immunology Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Google Scholar
Angi El-Wakeel
  • Angi El-Wakeel
  • Pediatric Critical Care Unit, Pediatric department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Google Scholar
Mohamed El-Assmy
  • Mohamed El-Assmy
  • Pediatric Critical Care Unit, Pediatric department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Google Scholar
Ghada Barakat
  • Ghada Barakat
  • Pediatric Critical Care Unit, Pediatric department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
  • Google Scholar
Wafaa Soliman
  • Wafaa Soliman
  • Microbiology Department, Faculty of Pharmacy, Delta University for Science and Technology, Egypt.
  • Google Scholar


  •  Received: 13 May 2016
  •  Accepted: 25 July 2016
  •  Published: 21 August 2016

References

Alfaleh K, Anabrees J, Bassler D, Al-Kharfi T (2014). Probiotics for prevention of necrotizing enterocolitis in preterm infants. Evid. Based. Child Health 3:584-671.
Crossref

 

Banupriya B, Biswal N, Srinivasaraghavan R, Narayanan P, Mandal J (2015). Probiotic prophylaxis to prevent ventilator associated pneumonia (VAP) in children on mechanical ventilation: an open-label randomized controlled trial. Intensive Care Med. 41:677-685.
Crossref

 

Besselink MGH, van Santvoort HC, Buskens E, et al (2008). Probiotic prophylaxis in predicted severe acute pancreatitis: a randomized, double-blind, placebo-controlled trial. Lancet. 371:651-659.
Crossref

 

Brandtzaeg P (1992). Humoral immune response patterns of human mucosae: induction and relation to bacterial respiratory tract infections. J. Infect. Dis. 165:167-176.
Crossref

 

Caceres P, Montes S, Vega N, Cruchet S, Brunser O, Gotteland M (2010). Effects of Lactobacillus rhamnosus HN001 on acute respiratory infections and intestinal secretory IgA in children. J. Pediatr. Infect. Dis. 5 (4):353-362.

 

Cernada M, Brugada M, Golombek S, Vento M (2014). Ventilator-associated pneumonia in neonatal patients: an update. Neonatology. 105:98-107.
Crossref

 

Duffy LC (2000). Interactions mediating bacterial translocation in the immature intestine. J. Nutr. 130:432-436.

 

Foglia E, Meier MD, Elward A (2007). Ventilator-associated pneumonia in neonatal and pediatric intensive care unit patients. Clin. Microbiol. Rev. 20:409-425.
Crossref

 

Forestier C, Guelon D, Cluytens V, Gillart T, Sirot J, De Champs C (2008). Oral probiotic and prevention of Pseudomonas aeruginosa infections: a randomized, double-blind, placebo controlled pilot study in intensive care unit patients. Crit. Care. 12(3):R69.
Crossref

 

Gluck U, Gebbers JO (2003). Ingested probiotics reduce nasal colonization with pathogenic bacteria (Staphylococcus aureus, Streptococcus pneumoniae, and β-hemolytic streptococci). Am. J. Clin. Nutr. 77:517-520.

 

Griffiths EA, Duffy LC, Schanbacher FL, Qiao H, Dryja D, Leavens A, Rossman J, Rich G, Dirienzo D, Ogra PL (2004). In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice. Dig. Dis. Sci. 49:579-589.
Crossref

 

Hao Q, Lu Z, Dong BR, Huang CU, Wu T (2011). Probiotics for preventing acute upper respiratory tract infections. Cochrane Database of Systematic Reviews (9):CD006895.
Crossref

 

Hojsak I, Abdović S, Szajewska H, Milosević M, Krznarić Z, Kolacek S (2010). Lactobacillus GG in the prevention of nosocomial gastrointestinal and respiratory tract infections. Pediatrics 125:1171-1177.
Crossref

 

Hojsak I, Tokić Pivac V, Močić Pavić A, Pasini AM, Kolaček S (2015). Bifidobacterium animalis subsp. lactis fails to prevent common infections in hospitalized children: a randomized, double-blind, placebo-controlled study. Am. J. Clin. Nutr. 101:680-684.
Crossref

 

Honeycutt TC, El Khashab M, Wardrop III RM, McNeal-Trice K, Honeycutt AL, Christy CG, Mistry K, Harris BD, Meliones JN, Kocis KC. (2007). Probiotic administration and the incidence of nosocomial infection in pediatric intensive care: A randomized placebo-controlled trial. Pediatr. Crit. Care Med. 8:452-458.
Crossref

 

Klarin B, Molin G, Jeppson B, Larsson A (2008). Use of the probiotic Lactobacillus plantarum 299 to reduce pathogenic bacteria in the oropharynx of intubated patients: a randomized controlled open pilot study. Crit Care. 12(6):R136.
Crossref

 

Klingberg TD, and Budde BB (2006). The survival and persistence in the human gastrointestinal tract of five potential probiotic lactobacilli consumed as freeze-dried cultures or as probiotic sausage. Int. J. Food Microbiol. 109:157-159.
Crossref

 

McNabb B, Isakow W (2008). Probiotics for the prevention of nosocomial pneumonia. Curr. Opin. Pulm. Med. 14:168-175.
Crossref

 

Merenstein D, Murphy M, Fokar A, Hernandez RK, Park H, Nsouli H, Sanders ME, Davis BA, Niborski V, Tondu F, Shara NM (2010). Use of a fermented dairy probiotic drink containing Lactobacillus casei (DN-114 001) to decrease the rate of illness in kids: the DRINK study. A patientoriented, double-blind, cluster-randomized, placebocontrolled, clinical trial. Eur. J. Clin. Nutr. 64(7):669-677.
Crossref

 

Mihatsch WA, Vossbeck S, Eikmanns B, Hoegel J, Pohlandt F (2010). Effect of Bifidobacterium lactis on the incidence of nosocomial infections in very-low-birth-weight infants: a randomized controlled trial. Neonatology 98:156-163.
Crossref

 

Pitsouni E, Alexious V, Saridakis V, Peppas G, Falagas M (2009). Does the use of probiotics/synbiotics prevent postoperative infections in patients undergoing abdominal surgery? A meta-analysis of randomized controlled trials. Euro. J. Pharmacol. 65:561-570.
Crossref

 

Rautava S, Salminen S, Isolauri E (2009). Specific probiotics in reducing the risk of acute infections in infancy--a randomised, double-blind, placebo-controlled study. Br. J. Nutr. 101(11):1722-1726.
Crossref

 

Rerksuppaphol S, Rerksuppaphol L (2012). Randomized controlled trial of probiotics to reduce common cold in school children. Pediatr. Int. 54(5):682-687.
Crossref

 

Rio ME, Zago Beatriz L, Garcia H, Winter L (2002). The nutritional status change the effectiveness of a dietary supplement of lactic bacteria on the emerging of respiratory tract diseases in children. Arch. Latinom Nutr. 52(1):29-34.

 

Rojas MA, Lozano JM, Rojas MX, et al (2012). Prophylactic probiotics to prevent death and nosocomial infection in preterm infants. Pediatrics 130:1113-1120.
Crossref

 

Sanz JMC, Mateos JA, Conejo AM (2006). Effect of Lactobacillus casei on the incidence of infectious conditions in children. Nytr. Hosp. 21(4):547-551.

 

Sohn AH, Garrett DO, Sinkowitz-Cochran RL, Grohskopf LA, Levine GL, Stover BH, Siegel JD, Jarvis WR (2001). Pediatric Prevention Network. Prevalence of nosocomial infections in neonatal intensive care unit patients: results from the first national point-prevalence survey. J. Pediatr. 139:821-827.
Crossref

 

Szajewska H (2011). Short- and long-term effects of probiotics administered early in life. Nestle Nutr. Workshop Ser. Pediatr. Program 68:65-78.
Crossref

 

Szajewska H, van Goudoever JB (2014). To give or not to give probiotics to preterm infants. Am. J. Clin. Nutr. 100:1411-1412.
Crossref

 

Taori RN, Lahiri KR, Tullu MS (2010). Performance of PRISM (Pediatric Risk of Mortality) score and PIM (Pediatric Index of Mortality) score in a tertiary care pediatric ICU. Indian J. Pediatr. 77:267-271.
Crossref

 

Wang YB, Du W, Fu AK, Zhang XP, Huang Y, Lee KH, Yu K, Li WF, Li YL (2016). Intestinal microbiota and oral administration of Enterococcus faecium associated with the growth performance of new-born piglets. Benef. Microbes. 19:1-10.
Crossref

 

Wolvers D, Antoine JM, Myllyluoma E, Schrezenmeir J, Szajewska H, Rijkers JT (2010). Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of infections by probiotics. J. Nutr. 140:698-712.
Crossref