November 2023
Effectiveness of temocillin on extended-spectrum beta-lactamase producing Escherichia coli isolates from patients attending the Niamey General Reference Hospital
Extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli urinary tract infections represent a major global health problem, constituting a public health emergency with high patient morbidity and mortality. Temocillin serves as an alternative antibiotic for treating these infections and conserving carbapenems. A total of 209 isolates of uropathogenic Escherichia coli were collected in the Microbiology Laboratory...
November 2023
Evaluation of the impact of the efflux pump modulation process on the anti-adhesion and antibiofilm activities of analogues of natural marine compounds in a marine bacterium
One strategy for enhancing the effect of natural marine antifouling compounds has been to combine them with coumarin-type molecules (VL2, VL17 and VL19). These molecules are known to have an inhibitory effect on the efflux pumps (EP) of a large number of Gram-negative bacteria. To this end, they have been used as adjuvants to natural marine compounds (OB1, AS194 and AS162) to enhance their antibiofilm activity. On the...
November 2023
Denaturing gradient gel electrophoresis (DGGE): An alternative culture independent method for bacterial screening in bovine milk sample
Bovine mastitis is a disease that has a great impact on Brazilian livestock production. Some bacteria described as mastitis-causing agents are not easily cultivable in conventional media, making their diagnosis difficult. The aim of the present study was to detect bacteria present in milk from mastitic and non-mastitic quarters of dairy cattle in Rio de Janeiro-Brazil, using a culture-independent and culture-dependent...
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