July 2021

Synthesis of N-alkyl-3- (1H-benzimidazolyl) -2-chloroquinoline derivatives potential candidates against infectious organisms

In the search for new drugs possessing the activities we have sought to synthesize new quinoline derivatives which constitute a basic heterocyclic support of some drugs such as quinine, chloroquine marketed under the name Nivaquine®, Mefloquine®, used in the treatment of malaria. The objective of this work is to contribute to the synthesis of new derivatives of quinoline. It consists in introducing heterocycles...

Author(s): Gbe Gondo Didier DIOMANDE, Sagne Jacques AKPA, Doumade ZON  and Ané ADJOU