African Journal of
Pure and Applied Chemistry

  • Abbreviation: Afr. J. Pure Appl. Chem.
  • Language: English
  • ISSN: 1996-0840
  • DOI: 10.5897/AJPAC
  • Start Year: 2007
  • Published Articles: 364

Table of Content: October 2015; 9(10)

October 2015

Comparative study of 1,3-dibromo-5,5-dimethylhydantoin assisted and conventional synthesis of benzimidazole derivatives and the solvent effects on spectroscopic properties

A small library of benzimidazoles with a range of side-chain substituents have been synthesized through the condensation reaction of o-phenylenediamine derivatives and several other commercially available materials. The reactions were catalyzed by either 4M HCl or 1,3-dibromo-5,5-dimethylhydantoin (DBDMH). The compounds synthesized using DBDMH as the catalyst required a shorter reaction time, the yield was higher and...

Author(s): Peter Adekunle Segun