African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2298

Full Length Research Paper

Effect of oral supplementation of Aloe vera extract on haematology indices and immune cells of blood in rabbit

Amjad Ali Channa*
  • Amjad Ali Channa*
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.
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Izhar Hyder Qazi
  • Izhar Hyder Qazi
  • Department of Veterinary Anatomy and Histology, Faculty of Bio-Sciences, Shaheed Benazir Bhutto University of Veterinary and Animal Sciences, Sakrand, Pakistan.
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Saeed Ahmed Soomro
  • Saeed Ahmed Soomro
  • Department of Veterinary Physiology and Biochemistry, Sindh Agriculture University, Tandojam, Pakistan.
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Atta Hussain Shah
  • Atta Hussain Shah
  • Department of Animal Products Technology, Sindh Agriculture University, Tandojam, Pakistan.
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Jameel Ahmed Gandahi
  • Jameel Ahmed Gandahi
  • Department of Veterinary Anatomy and Histology, Sindh Agriculture University, Tandojam, Pakistan.
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Roshan Ali Korejo
  • Roshan Ali Korejo
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.
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Imtiaz Ahmed Shah
  • Imtiaz Ahmed Shah
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.
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Nawab Ali Kalhoro
  • Nawab Ali Kalhoro
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.
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Band-e-ali Khaskeli
  • Band-e-ali Khaskeli
  • Faculty of Animal Husbandry and Veterinary Sciences, Sindh Agriculture University, Tandojam, Pakistan.
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  •  Received: 01 January 2014
  •  Accepted: 24 April 2014
  •  Published: 22 May 2014

Abstract

Aloe vera is being widely used in herbal medicine as antibacterial, antiviral, antifungal, and antiinflammatory agent. It is also used as topical application for many skin diseases; its antidiabetic effect in rats is also reported. Looking at its enormous medicinal effects, the present study was conducted to investigate the effects of oral supplements of Aloe vera extract on hemotology indices and immune cells of rabbit. Total of twenty (n=20) rabbits were selected and divided into 4 group’s i-e A, B, C and D with n=5 in each group. Group A was kept as control while B, C and D were given 400, 500 and 600 mg/kg of Aloe vera extract, respectively daily for 21 days. Blood samples were collected from central ear vein transferred into test tubes containing ethylene diamine tetra acetate (EDTA) on 0 day, 7th day, 14th day and 21st day and analysed for complete blood count (CBC). Results revealed that oral supplementation of A. vera extract significantly increase mean corpuscular haemoglobin (MCH), mean corpuscular volume (MCV) and lymphocytes at level (p< 0.05) and decrease neutrophils in normal domestic rabbits. Results of this study concluded that A. vera has hematopoetic and immunomodulatory effects; thus its extract can be used for the treatment of anemia and immune deficiency problems.

 

Key words: Aloe vera, biological active, anaemia, immunodeficiency.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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