African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2241

Full Length Research Paper

Lycium barbarum polysaccharides (LBP) extraction technology and its antioxidation activity

Ling Yuan1,2, Yi Nan3, Rong Wang3 and Yang Niu3*
1Pharmacy College of Ningxia Medical University, Yinchuan, Ningxia Province.750004, People’s Republic of China. 2Minority Traditional Medical Center of Minzu University of China, Beijing.100081, People’s Republic of China. 3Traditional Chinese Medicine College of Ningxia Medical University, Yinchuan City, Ningxia Province, 750004, People’s Republic of China.
Email: [email protected]

  •  Accepted: 07 May 2012
  •  Published: 22 May 2013

Abstract

This study was carried out to investigate the technology of extracting Lycium barbarumpolysaccharide (LBP) and its antioxidation activity, using orthogonal experimental method to optimize its extraction conditions. Fenton reaction and pyrogallol experimental method were adopted to determine the antioxidation activity of LBP. The three factors investigated in the orthogonal experiment affected the results. Different concentrations of LBP effectively cleared hydroxyl radical (OH-) and superoxide anion (O2+). It was concluded that the extraction of LBP by cold maceration as well as the three factors, (solvent volume, extraction time and extraction times) affects its yield, and that it has antioxidation activity.

 

Key words: Lycium barbarum polysaccharides, antioxidation activity.