African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2296

Full Length Research Paper

Immunomodulatory potential of Phlomis bracteosa

Riaz Ullah1,2, Yousef Saleh Al-Zeghayer2 and Sajjad Haider2
1Department of Chemistry, Kohat University of Science and Technology, Kohat-26000, KPK, Pakistan. 2Department of Chemical Engineering, College of Engineering, King Saud University, P.O BOX 800, Riyadh 11421, Kingdom of Saudi Arabia.
Email: [email protected]

  •  Accepted: 16 September 2011
  •  Published: 22 October 2011

Abstract

The present study reports the immunomodulatory activities of different crude fractions ofPhlomis bracteosa. In case of immunomodulatory study, the ethylacetate fraction demonstrated significant modulatory effect for oxidative burst of polymorphoneutrophils and CHCl3 crude fraction for the whole blood, while the aqueous fraction demonstrated reasonable inhibition. Hence, both the chloroform and ethylacetate fractions of P. bracteosaare suggested further for the isolation and identification of active constituents responsible for the observed effects.

 

Key words: Phlomis bracteosa, lamiaceae, immunmodulatory potential.

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