October 2014
Simultaneous determination of valsartan and hydrochlorothiazide in a tablet dosage form by liquid chromatography
A selective, rapid and accurate liquid chromatographic method is described for the simultaneous determination of valsartan (VAT) and hydrochlorothiazide (HTZ) in a solid dosage form. The chromatographic separation of two drugs were achieved on Lichrosphere CN column 250 mm × 4.0 mm,5 µm, Merck-India. The mobile phase consisting mixture of methanol, isopropyl alcohol and n-hexane in the ratio of 50:25:25 v/v...
October 2014
Effects of Salicornia herbacea L. supplementation on lipid peroxidation and antioxidative protein expression in rat skeletal muscle
Effects of Salicornia herbacea L. supplementation on lipid peroxidation and antioxidative protein expression in the skeletal muscle of rats was investigated in this study. Sixteen 6-week-old Sprague Dawley male rats were randomly divided into a control diet group (CG, n = 8) and an experimental diet group (EG, n = 8). The rats were given a high-fat diet (CG) or the 5% S. herbacea L. supplemented high-fat diet (EG) for 8...
October 2014
Influence of polyethylene glycol-8-lauryl ester in the structural lipid of the elastic liposomes
This study compared the physicochemical characteristics of conventional and elastic liposomes in terms of surfactant incorporation, flow rate, elasticity, mean diameter, phospholipid content and permeation capability. Surfactants were incorporated into conventional liposomes in order to enhance the transdermal transport of drugs through the stratum corneum. The unilamellar liposomes produced composed of egg...
October 2014
Preliminary investigations of the binding ability of lima bean (Phaseolus lunatus) starch in paracetamol tablets
The binding properties of starch obtained from Lima bean (Phaseolus lunatus) were evaluated. The starch from the seeds was extracted and the binding ability of its mucilage compared with that of maize starch mucilage in paracetamol based tablets at concentrations of 0, 2.5, 5, 7.5 and 10% w/v. The following properties of the starch powders were evaluated; organoleptic properties, microscopy and reaction with iodine...
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