April 2015

Comparison of the efficacy and safety of an oral combination of losartan, hydrochlorothiazide and simvastatin against separated components, in hypertensive and dyslipidemic patients

Hypertension is an important health problem that frequently requires multidrug treatment, whether due to monotherapy failure or in a concomitant manner. This situation has impulsed the development of some fixed dose combination products with the idea of improve the efficacy, the safety or the adherence of the treatment. In this study, the efficacy and safety of a fixed dose combination product composed by losartan,...

Author(s): Emilio Exaire-Murad, Luis Fernando Paredes-Fernández, Jorge Antonio Aldrete-Velasco, Elvira Isabel Nuño-Carral, Juan Gerardo Reyes García, Francisco Javier Flores-Murrieta, Miriam del Carmen Carrasco-Portugal and Noemí Santos-Caballero  

April 2015

Genotoxicity and anti-genotoxicity of aqueous extracts of herbal recipes containing Luffa cylindrica (L), Nymphaea lotus (L) and Spondias mombin (L) using the Allium cepa (L) assay

Management of diseases with medicinal plant is an ancient practice that has improved in recent years. Extracts of Luffa cylindrica (Linn), Nymphaea lotus (Linn) and Spondias mombin (Linn) are used for traditional management of cancer in Nigeria. Four recipes prepared from the combinations of two or three of these plants; L. cylindrica, N. lotus and S. mombin (LNS), N. lotus and S. mombin (NS), N. lotus and L. cylindrica...

Author(s): S. M. Atoyebi, I. T. Oyeyemi, B. A. Dauda and A. A. Bakare