African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2285

Table of Content: 22 December, 2012; 6(47)

December 2012

Evaluation of the blood pressure lowering activity of leaf extract of Acalypha torta Muell

The leaf of Acalypha torta Muell. (Euphorbiaceae) is used as folk remedy in Nigeria for the treatment of hypertension. Effects of extracts of A. torta leaf on the blood pressure of anaesthetized cats were studied to examine this claim. The ethanol extract produced a significant (p < 0.0001) and dose - dependent fall in arterial blood pressure. The extract inhibited adrenaline - induced contraction...

Author(s): C. N. Ezekwesili, S. Ghasi and O. F. C. Nwodo

December 2012

Clinical efficacy of cefixim compared to amoxicillin- clavulanate in community acquired pneumonia treatment

Due to the lack of availability of respiratory fluoroquinolones, treatment using amoxicillin- clavulanate is recommended for community acquired pneumonia (CAP) in Iran. Cefixime offers advantages such as lower cost and improved patients compliance. The current study was designed to compare the therapeutic effects of amoxicillin- clavulanate and cefixime in patients with CAP. In a randomized...

Author(s): Nader Zarinfar, Hossein Sarmadian and Akram Esmaeili

December 2012

Studies on the effect of gold nanoparticles on oxidative stress and antioxidants defense indices in various rat tissues

Gold nanoparticles (AuNPs) have a wide range of applications in various fields. It is therefore essential to study their interaction with the biological system. In the present study, the effect of AuNP was studied on oxidative stress and antioxidants in various tissues of rats. In this study, liver was the organ most sensitive to the effects of AuNP. Liver of AuNP treated rats showed a significant increase in lipid...

Author(s): Nikhat Jamal Siddiqi, Mohammad Anwar Kasim Abdelhalim, Yusra Ahmed AlYafeeand Abdullah Salih Alhomida

December 2012

Determination of volatile aroma compounds of Antrodia juniperina

Antrodia juniperina is one of the most common Antrodia genus species in Turkey, which is regarded as a medicinal plant in some countries. The aim of this study is to determine the volatile aroma compounds (compounds) of A. juniperina. The volatile aroma compounds of A. juniperina were analyzed by headspace gas chromatography (GC-MS). 22 volatile compounds such as alcohols, aldehyde, acids,...

Author(s): Hasan Hüseyin DoÄŸan, Hatıira TaÅŸkıin, Ebru Kafkas and Saadet Büyükalaca

December 2012

Angiotensin receptor blockers in preventing stroke: A systematic review and meta-analysis of randomized controlled trials

Angiotensin converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) are widely used in patients who are at high risk of cardiovascular events. A consensus has emerged that ACEIs can reduce the risk of stroke. This programme of overviews of randomized trials was established to investigate the effects of ARBs on the risk of stroke in patients at risk for cardio-cerebrovascular events. Electronic...

Author(s): Yan-Bing Duan, Xiao-He Lu and Zheng-Quan Wang

December 2012

Investigation of fatty acid composition of Ammi visnaga seed oil by gas chromatography-mass spectrometry (GC-MS)

The Ammi visnaga seeds oil constituents of methyl ester derivatives of fatty acids were analyzed using gas chromatography coupled with mass spectrometer. The results obtained contain saturated as well as unsaturated fatty acids of A. visnaga seeds oils. A total of 15 different components were identified and quantified. Methyl ester of oleic acid was found in high concentration (13.30%) among the identified analytes of...

Author(s): Riaz Ullah, Iqbal Hussain, Jameel Ahmad Khader, Naser Mohamed AbdEIslam, Tayyeba Samreen