October 2014

Determination of some mineral and heavy metals in Saudi Arabia popular herbal drugs using modern techniques

  The contents of 22 essential mineral elements and trace, heavy and toxic metals in 14 herbal drugs collected from the local markets of the western province of Saudi Arabia have been determined. All investigated elements were detected using inductively coupled plasma–atomic emission spectrometer (ICP-AES) after pretreatment of the tested samples with microwave digestion system. The levels of the most...

Author(s): Ibrahim A. Maghrabi

October 2014

Evaluation of the anti-ulcer property of aqueous extract of unripe Musa paradisiaca Linn. peel in Wistar rats

  This study investigated the antiulcer activity of aqueous extract of unripe Musa paradisiacal (plantain) peels in rats using ethanol, aspirin, indomethacin and pyloric ligation-induced ulcer models. Fresh peels of M. paradisiaca were extracted in hot water and the yield lyophilised. Distilled water, standard drugs and extract were injected intraperitoneally before inducing ulcer. Lethality test and...

Author(s): Ezekwesili Chinwe N., Ghasi, S., Adindu Chukwuemeka S. and Mefoh Nneka C.

October 2014

Effect of co-administration of artemether and nevirapine on haematological parameters in normal and immunosuppressed Wistar rats

Artemether and nevirapine are effective drugs used in the treatment of malaria and as part of antiretroviral therapy, respectively in many parts of the world. However, concomitant use of these drugs may pose an adverse drug interaction that may alter their pharmacological effects. In this study, possible effect(s) of artemether-nevirapine co-administration on haematological indices in both normal and immune-compromised...

Author(s): S. B. Anafi, H. O. Kwanashie, J. A. Anuka, H. M. Muktar and A. S. Agbaji