November 2018

Effects of combination therapy of Bridelia ferruginea stem bark and diminazene aceturate on testicular and haematological changes in Trypanosoma brucei infected male rats

The study was done to assess the ameliorative effects of co-administration of methanol extract of Bridelia ferruginea stem bark and diminazene aceturate on trypanosomosis induced testicular and haematological changes in infected male rat. Twenty five male rats were used in the study and assigned into five groups (n=5). Trypanosoma brucei was inoculated into Groups 1, 2, 3 and 4 rats except Group 5. Diminazene aceturate...

Author(s): Odo Rita Ifeoma, Ihedioha Thelma Ebele and Ukpai Ebubechi Emmanuel  

November 2018

The protective effects of Vitamin E and glibenclamide on spermatogenic and haematological changes in alloxan-induced diabetic male rats

This study was designed to evaluate the preventive potentials of vitamin E and glibenclamide on spermatogenic and haematological damages in alloxan-induced diabetic male rats. Thirty mature male albino rats randomly assigned into 5 groups (n=6) were used for the study. Diabetes was experimentally induced in groups 1 to 4 while group 5 rats served as the negative control. Rats in groups 1, 2 and 3 were treated with...

Author(s): R. I. Odo, N. E. Ugwu and S. Akusu