May 2008
The anticonvulsant and sedative properties of stems of Cissus quadrangularis in mice
Cissus quadrangularis Linn grows in Savannah areas in Africa (Cameroon, Mali, Mauritania, Senegal, etc). In traditional medicine, the plant is used to treat anorexia, asthma, sickle cells, colds, pains, malaria, asthma and as an analgesic. In vivo animal models of epilepsy (maximal electroshock, n-methyl -d-aspartate, pentylenetetrazol, isonicotinic hydrazid acid and strychnine -induced convulsions or turning...
May 2008
Effects of Cucumis metuliferus E Mey. Ex Naud (Cucurbitaceae) fruit extract on some male reproductive parameters in adult rats
The effect of the extract of Cucumis metuliferus fruit on some male reproductive parameters was investigated in albino rats. The LD50 of the extract was above 5000 mg/kg body weight when administered orally. Histological studies showed that there was no remarkable change in the testes histology compare to the control. The effects on sperm cells showed a statistically significant (P<0.05) increase in...
May 2008
Performance of starch obtained from Dioscorea dumetorium as disintegrant in sodium salicylate tablets
Starch obtained from Dioscorea dumetorium was employed as a disintegrant in Sodium Salicylate based tablets at concentrations of 5 –15 %w/w. Properties of the starch evaluated include: bulk and tapped densities, water uptake by capillarity, Hausner’s quotient and percent compressibility. Compound tablets were evaluated for hardness, friability, disintegration time and dissolution rate. Batches of...
May 2008
Citalopram in the treatment of depressive disorders: An open label, multicenter study in China
Results of randomized, placebo-controlled trials with the selective serotonin reuptake inhibitor citalopram suggest that this agent is safe and effective for the treatment of depressive disorders. We investigated the safety and efficacy of citalopram in the treatment of Chinese patients with depressive disorders. An 8-week, open-label, multicenter study evaluated the safety and efficacy of citalopram in the treatment of...
May 2008
Current status of salt iodization and level of iodine nutrient in India
In India, Iodine Deficiency Disorders (IDD) are present throughout the country. Out of 282 districts surveyed by Government of India institutions like Indian Council of Medical Research and Central Goitre Survey Teams in different States and Union Territories, 241 have been found to be endemic for iodine deficiency disorders. Issues relating to the safety of Universal Salt Iodization were carefully examined by eminent...
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