November 2008
Proniosome based drug delivery system of piroxicam
Piroxicam is a widely used potent non-steroidal anti-inflammatory drug, with due potential for dermal delivery. Permeation of piroxicam from proniosome based reservoir type transdermal gel formulation across excised rat abdominal skin was investigated using Keshery Chein diffusion cell. There was considerable improvement in flux over the control gel formulation. The lipid vesicles were evaluated for entrapment...
November 2008
Anti-Inflammatory and antipyretic effects of an ethanolic extract of Palisota hirsuta K. Schum roots
The effect of Palisota hirsuta root ethanolic extract, a herbal preparation used in Ghana for pain and inflammatory disorders, was assessed in acute inflammation in carrageenan-induced foot oedema in chicks and brewer’s yeast-induced pyrexia in rats. Two paradigms were used for the inflammation assessment; effect of the extract on established inflammation (curative protocol) and effect before the induction of...
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