International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 537

Full Length Research Paper

A retrospective study on the outcomes of tuberculosis treatment in Felege Hiwot Referral Hospital, Northwest Ethiopia

Fantahun Biadglegne
  • Fantahun Biadglegne
  • Faculty of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.,Institute of Medical Microbiology and Epidemiology of Infectious Diseases, University Hospital, University of Leipzig, Leipzig, Germany.,Institute of Clinical Immunology, University Hospital, University of Leipzig, Leipzig, Germany.
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Berhanu Anagaw
  • Berhanu Anagaw
  • Faculty of Science, Addis Ababa University, Addis Ababa, Ethiopia.
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Tewodros Debebe
  • Tewodros Debebe
  • Faculty of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
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Belay Anagaw
  • Belay Anagaw
  • College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
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Woghata Tesfaye
  • Woghata Tesfaye
  • College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
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Belay Tessema
  • Belay Tessema
  • Institute of Medical Microbiology and Epidemiology of Infectious Diseases, University Hospital, University of Leipzig, Leipzig, Germany.,Institute of Clinical Immunology, University Hospital, University of Leipzig, Leipzig, Germany.,College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
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Arne C. Rodloff
  • Arne C. Rodloff
  • Institute of Medical Microbiology and Epidemiology of Infectious Diseases, University Hospital, University of Leipzig, Leipzig, Germany.
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Ulrich Sack
  • Ulrich Sack
  • 3Institute of Clinical Immunology, University Hospital, University of Leipzig, Leipzig, Germany.,Fraunhofer Institute for Cell Therapy and Immunology, Leipzig, Germany.,Translational Centre for Regenerative Medicine (TRM), University of Leipzig, Leipzig, Germany.
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  •  Accepted: 16 November 2012
  •  Published: 28 February 2013

Abstract

In this study, we investigated the outcomes of tuberculosis treatment at Felege Hiwot Referral Hospital in northwest Ethiopia. According to the World Health Organization (WHO), treatment outcome is an important indicator for tuberculosis (TB) prevention and control programme. We analyzed the records of 756 tuberculosis patients registered for treatment in Felege Hiwot Referral Hospital from January, 2010 to 2012. From the total of 756 TB patients, 331 (43.8%) were pulmonary tuberculosis (PTB) and 425 (56.2%) were extrapulmonary tuberculosis (EPTB) cases. Among the study subjects, 191 (25%) were Human immunodeficiency virus (HIV) seropositive. Of all patients, treatment outcome was classified as successfully treated 193 (26%), defaulted in 19 (2.5%), died in 44 (5.8%), treatment failed in 4 (0.5%) and transferred out in 496 (68.6%) patients. The percentage of deaths and defaulters was higher in females than in males. Being an older age group (p = 0.004), a rural resident (p = 0.000) and EPTB patients (p = 0.004) were associated with a lower treatment success rate, which are serious public health concerns that need to be addressed urgently. Therefore, treatment plans that emphasize Directly observed treatments(DOTS) for at-risk patients have the greatest success in improving tuberculosis treatment outcome in the region. Urgent need for strengthening treatment outcome monitoring to ensure effective program implementation and case management system in the study area is strongly recommended.

 

Key words: Treatment outcomes, tuberculosis patients, northwest Ethiopia.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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