International Journal of
Medicine and Medical Sciences

  • Abbreviation: Int. J. Med. Med. Sci.
  • Language: English
  • ISSN: 2006-9723
  • DOI: 10.5897/IJMMS
  • Start Year: 2009
  • Published Articles: 531

Full Length Research Paper

Nosocomial methicillin-resistant Staphylococcus aureus bacteremia in a tertiary care hospital: Risk factors, overall mortality and antimicrobial resistance

Rosineide Marques Ribas
  • Rosineide Marques Ribas
  • Universidade Federal de Uberlândia, Laboratório de Microbiologia, Uberlândia, Minas Gerais, Brazil.
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Claudete Freitas
  • Claudete Freitas
  • Universidade Federal de Uberlândia, Laboratório de Microbiologia, Uberlândia, Minas Gerais, Brazil.
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P. Paulo Gontijo Filho
  • P. Paulo Gontijo Filho
  • Universidade Federal de Uberlândia, Laboratório de Microbiologia, Uberlândia, Minas Gerais, Brazil.
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  •  Accepted: 16 September 2009
  •  Published: 30 October 2009

Abstract

A retrospective study on risk factors of Staphylococcus aureus bacteremia was carried out on 99 blood culture isolated episodes of S. aureus in a Brazilian hospital during 2000 - 2002”. We found several factors associated with an increased risk of methicillin-resistant S. aureus(MRSA) bacteremia including presence of two or more devices and use of antimicrobials. The patients with MRSA bacteremia were most likely to be in the surgical wards, but those with MSSA bacteremia were most likely to be in the internal medical ward. Overall mortality rate was 33.3%. Among 99 patients with episodes of S. aureus bacteremia, 25 died (25.3%) within 15 days of onset. Our research shows that MRSA bacteremia was more likely to be associated with extrinsic factors.

Key words: Staphylococcus aureus bacteremia, nosocomial MRSA, risk factors, epidemiologic study.