A cross sectional comparative study was performed in Lahore city to evaluate the changes of the serum lipid profile in healthy adolescent male non smokers and smokers’ subjects. A total of 100 subjects with age range 14 - 19 years were selected and grouped as non smokers (control) and smokers with 50 cases in each. Biochemical analysis of fasting serum lipid profile of each group was assessed using spectrophotometer. By applying independent sample t-test, significant differences were observed in TG, HDL-C and LDL-C and by applying chi-square (χ2) test, significant association of TC, TG, HDL-C and LDL-C were found among smokers and controls. From the results of the present study, it may be concluded that, cigarette smoking during adolescent period induces alteration in serum lipid levels in the direction of increased risk for coronary artery disease.
Key words: Total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol.
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