August 2009
Health disparity– a concern
August 2009
Regulation of tubulin expression: Multiple overlapping mechanisms
Tubulin is the main constituent of microtubules, a macromolecule participating in a variety of essential cell phenomena. Although the roles of microtubules have been extensively described, the regulation of tubulin expression remains largely unexplored. This review gives an overall view of the regulatory mechanisms of tubulin expression reported in the literature. The first model proposed to explain the regulation...
August 2009
Pemphigus vulgaris associated with significant periodontal findings: A case report
The purpose of this article is to report a case of Pemphigus vulgaris (PV) associated with periodontitis and role of dermatologist and periodontist in its management in the routine practice. Periodontitis is a plaque induced inflammation involving and destroying the supporting alveolar bone, cementum and periodontal ligament. Pemphigus is a group of bullous diseases that affect the oral mucosa and...
August 2009
End stage renal disease patient presenting with breast pain: Case report
Key words: Calciphylaxis, end stage renal disease, breast necrosis, breast pain, secondary hyperparathyroidism
August 2009
Efficacy and safety of curative catheter ablation for atrial fibrillation
Atrial fibrillation (AF) is the most common arrhythmia in clinical practice. Its treatment is still widely debated due to the large variety of therapeutic options. Radiofrequency catheter ablation (RFCA) around pulmonary vein ostia and in left atrium has been proposed as a curative technique to treat AF and is now performed with increasing success worldwide. However, few randomised controlled trials (RCTs) are...
August 2009
Nutritional status of undergraduates in a Nigerian university in South-west Nigeria
The study evaluated the nutritional status and eating habits of undergraduate students in a Nigerian University. One hundred undergraduates (ages 15 to 40 years) of the Lagos State University, Ojo participated in the study. General information, anthropometric data, as well as a 7-day dietary recall were obtained by means of questionnaire. Venous blood samples were collected from the respondents and analyzed for vitamins...
August 2009
Prevalence and determinants of unmet need for family planning in Nnewi, South-east Nigeria
The unmeet need for family planning is a very useful tool in measuring and predicting the contraceptive needs of a population. A descriptive cross sectional study of 356 women attending the antenatal clinic of Nnamdi Azikiwe University Teaching Hospital, Nnewi, Nigeria, was carried out to determine the level of unmeet need and its determinants. Three hundred and forty (95.5%) of the respondents had knowledge about...
August 2009
Study of periodic breathing and human respiratory system
A theoretical study of respiratory stability, based on a simple CO2 and O2 model of the respiratory system has been investigated. A model of the human respiratory system is proposed which has a satisfactory performance under different physiological conditions. It is shown that the central component is not involved in respiratory instability phenomena such as periodic breathing whereas the peripheral...
August 2009
Awareness and knowledge of HIV/AIDS at booking among antenatal clinic attendees in Uyo, Nigeria
Sub-saharan Africa bears the major brunt of the global HIV/AIDS pandemic and 10% of these infections are due to vertical or mother-to-child transmission (MTCT). Interventions to prevent mother-to-child transmission (PMTCT) in the developed world have resulted in a dramatic decline in pediatric HIV/AIDS. A study of the awareness, knowledge and previous testing for HIV/AIDS among antenatal clinic attendees at the...
August 2009
Cerebrospinal fluid characteristics of PCR diagnosed enteroviral meningitis (EVM) in children
Distinguishing bacterial from viral meningitis helps prevent unnecessary use of antibiotics and decreases the length of stay. The distinction may often be blurred by the typical textbook description of viral meningitis which states that mononuclear cells predominate in the cerebrospinal fluid (CSF). The aim of the work is to accurately describe the CSF response in a group of children with enteroviral meningitis...
August 2009
Torsade de pointes in a patient with bronchopenumonia and atrial fibrillation treated with clarithromycin
Clarithromycin is a macrolide antibiotic widely used in pulmonary infection and Helicobacter pylori eradication. QT prolongation on an electrocardiogram with torsade de pointes is an uncommon fatal side effect. We report a patient with atrial fibrillation and congestive heart failure who develops torsade de pointes after clarithromycin, tamoxifen, amoxillin/clavulanate, digoxin and verapamil use, and discuss...
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