African Journal of
Bacteriology Research

  • Abbreviation: J. Bacteriol. Res.
  • Language: English
  • ISSN: 2006-9871
  • DOI: 10.5897/JBR
  • Start Year: 2009
  • Published Articles: 123

Full Length Research Paper

Antibiotic resistance patterns of Escherichia coli strains isolated from pig's (Sus scrofa domesticus) casings in Lomé, Togo

Yao Selom ATRAH
  • Yao Selom ATRAH
  • Higher School of Biological and Food Techniques, University of Lomé-Togo.
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Kossi Jacques DOUMEGNO
  • Kossi Jacques DOUMEGNO
  • Laboratory of Microbiology and Food Quality Control, University of Lomé-Togo.
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Sika DOSSIM
  • Sika DOSSIM
  • Laboratoire de Biologie Médicale CHU Kara, Togo.
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Essodina TALAKI
  • Essodina TALAKI
  • Higher School of Agricultural Sciences, University of Lomé-Togo.
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Yaovi AMEYAPOH
  • Yaovi AMEYAPOH
  • Laboratory of Microbiology and Food Quality Control, University of Lomé-Togo.
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Mounerou SALOU
  • Mounerou SALOU
  • Laboratoire Biolim, Faculty of Health Sciences, University of Lomé-Togo.
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  •  Received: 31 August 2021
  •  Accepted: 13 October 2021
  •  Published: 31 July 2024

Abstract

Optimal treatment and prudent use of antimicrobials for pigs is imperative to secure animal health and mostly prevent the development of critical resistance which can be transmitted to humans. An important step in this one-health context is to monitor resistance patterns of important animal pathogens. The aim of the study was to investigate the antibiotic resistance patterns of Escherichia coli strains in the intestinal flora of pigs in Lome, Togo. Thus 41 E. coli strains were isolated from 50 non duplicate samples of pig’s faeces collected in various pig’s casing in Lome. Disk diffusion antimicrobial susceptibility testing against a panel of antibiotics was carried out for the isolates. Susceptibility was interpreted using clinical breakpoints. Various resistance patterns were obtained. Both imipenem and fosfomycin were 100% sensitive; ampicillin, ofloxacin and nalidixic acid were the top three least active molecules on the isolated E. coli. The mean resistance rates were 10.8% for cephalosporins, 28% for penicillins, and 29.6% for other antibiotics. A total of 18 multidrug-resistant strains were found (43.9%). The resistance phenotypes found were: ESBL (4.9%), low level (14.6%) and high level (9.8%) penicillinase, low level (7.3%) and high level cephalosporinase (2.4%). With the presence of these critical resistant phenotypes, continuous surveillance of resistance patterns in pig pathogenic bacteria is urgent.

 

Key words: Escherichia coli, resistance, antibiotic, pig, Lome, Togo.