December 2017

Aqueous extract of Persea americana leaves ameliorates alloxan-induced hyperglycaemia and hyperlipidaemia in rats

Decoctions of Persea americana Mill (Lauraceae) leaves are employed to manage diabetes mellitus among the Ibo communities of Eastern Nigeria. In this study, we studied the ameliorative effects of the aqueous extract of P. americana leaves (AEPAL) on alloxan-induced hyperglycaemia and hyperlipidaemia in Wistar rats. The oral median lethal dose (LD50) of AEPAL was determined in rats. The effects of extract on blood...

Author(s): Stephen Chiadikaobi Okafor, Steven Samuel Gyang, Bilkisu Bello Maiha, Ejike Daniel Eze, Musa Itopa Yakubu and Ben Ahmed Chindo,

December 2017

Phytochemical screening and In Vivo antimalarial activities of crude extracts of Lantana trifolia root and Premna oligotricha leaves in plasmodium berghei infected mice

Resistance of malaria parasites to several antimalarial drugs mandates the need for new compounds from affordable sources. Thus the current study was conducted to justify the  traditional usage of Lantana trifolia roots and Premna oligotricha  leaves to combat malaria. The powdered roots of Lantana trifolia and leaves of Premna oligotricha  were macerated using 70% ethanol. Secondary metabolites present...

Author(s): Sisay Seyfe, Alemayehu Toma, Atkilt Esaiyas, Etana Debela,  Abraham Fikru and Amelework Eyado