March 2025

Chloroform and ethyl acetate extracts of Hedysarum alpinum L. mitigate the ketamine-induced behavioral dysfunction and oxidative stress in schizophrenia-like animals

The effects of chloroform and ethyl acetate extracts of Hedysarum alpinum L. were investigated through a ketamine-induced schizophrenia-like rat model. The quantitation of the total triterpene saponin content of extracts was determined by using oleanolic acid as standard. The ethyl acetate extract had a total triterpene saponin of 10.02 ± 0.02 mg otoacoustic emission (OAE)/g, while the chloroform extract had 8.50...

Author(s): Aldarmaa Jalsrai, Anu Altangerel, Myadagbadam Urtnasan and Hsiu Mei Hsieh-Li