Journal of
Parasitology and Vector Biology

  • Abbreviation: J. Parasitol. Vector Biol.
  • Language: English
  • ISSN: 2141-2510
  • DOI: 10.5897/JPVB
  • Start Year: 2009
  • Published Articles: 199

Article in Press

Coverage and effectiveness of Intermittent Preventive Treatment of Malaria with Sulfadoxine-Pyrimethamine during pregnancy in six sentinels’ sites of Côte d’Ivoire

Offianan Andre Toure1, Serge-Brice ASSI2 , Valerie Akoua BEDIA3, Landry Tiacoh N’GUESSAN 1, Thomas Yapo ABA4, Kalou Dibert ZIKA5 , Abibatou KONATE3, Pulcherie Marie Christiane KIKI-BARRO3, William YAVO3, Koffi Daho ADOUBRYN5, Eby Ignace Hervé MENAN3, Emmanuel BISSAGNENE 6

  •  Received: 31 May 2021
  •  Accepted: 29 July 2021
Intermittent preventive treatment of malaria during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) is recommended to prevent maternal and neonatal adverse outcomes. This study aimed to assess IPTp-SP coverage in mothers delivering in six health facilities and factors associated with placental malaria and low birth weight. A multicenter, cross-sectional survey was conducted in Côte d’Ivoire from March to October 2017. Regression logistics were used to study factors associated with placental malaria, IPTp-SP uptake, and LBW (<2.500 grams). Out of all the enrolled participants (n=1236), 632 (51.1) received three or more doses of SP while 288 (23.3%), 221 (17.9%) and 95 (7.7%) received respectively two, one and none dose of SP. Uptake of ? 3 doses varied significantly (p < 0.001) according to study site, number of ANC visits and profession. Regression analysis identified primigravidae, single dose IPTp-SP, or no IPTp-Sp as factors associated with placental malaria. IPTp-SP coverage observed in this study was low compared to WHO recommendation and contrasted with the high antenatal care (ANC) visits. There is a need for further research to understand the barriers and enablers of uptake in each context in order to improve uptake of adequate IPTp-SP regimen.

Keywords: Coverage, Effectiveness, Malaria, Pregnancy, IPTp-SP, Côte d’Ivoire