Journal of
Veterinary Medicine and Animal Health

  • Abbreviation: J. Vet. Med. Anim. Health
  • Language: English
  • ISSN: 2141-2529
  • DOI: 10.5897/JVMAH
  • Start Year: 2009
  • Published Articles: 400

Article in Press

ffects of piroxicam on ketamine anaesthesia in West African dwarf goats (capra hircus).

NWANKWO Henry Chuwkuebuka, ONYEYILI, Patrick Azubuike, SAGANUWAN and Saganuwan Alhaji

  •  Received: 22 February 2022
  •  Accepted: 09 May 2022
Ketamine produces an agitated state of anaesthesia when given alone, thus a pre-anaesthetic medication is very vital for smooth anaesthesia with ketamine. Piroxicam has been recorded to produce sedation. Thus piroxicam co-administered with ketamine was aimed to nullify the cataleptic effect of ketamine. Thirty West African Dwarf goats, grouped into five groups of six animals each, were used for the experiment. Group I was administered ketamine (10 mg.kg -1) only while group II, III, IV and V were administered piroxicam (5 mg./kg -1) 15, 30, 60 and 120 min prior to ketamine administration respectively. The sleeping time was measured; temperature, heart and respiratory rates and response to pinprick (analgesia) were recorded at intervals of 5, 10, 20, 30 and 45 min, respectively. Findings revealed very significant level of analgesia at perineum, flank and inguinal region in the 15 min (58.4 – 70.9 %), 30 min (50 – 70.9 %) and 60 min (45.8 – 75 %) post piroxicam administered groups as compared to ketamine only treated group (p ? 0.05). Heart and respiratory rates were significantly (P ? 0.05) increased throughout the period of experimentation. Piroxicam/ketamine combination could provide synergistic analgesia and increase duration of sleep with ketamine, and thus may provide improved anaesthesia for elective and emergency surgeries in goats in comparison with ketamine only.

Keywords: anaesthetic, analgesia, goats, ketamine, piroxicam