April 2014

Effect of co-culturing of cellulolytic fungal isolates for degradation of lignocellulosic material

This study intended to compare the efficiency of fungal monocultures and co-cultures in the simultaneous delignification and saccharification of kitchen waste and Eichhornia crassipes in order to subject the hydrolysate into biofuel production. Three fungal isolates of genus Trichoderma, Aspergillus, Pycnoporus and an unidentified strain (F113) were grown in mono and co-cultures and the extracted enzymes were...

Author(s): K. Mohanan, R.R. Ratnayake, K. Mathaniga, C. L. Abayasekara and N. Gnanavelrajah

April 2014

The Lap3p aminopeptidase is not solely responsible for bleomycin resistance in Candida albicans

Detoxification of the glycopeptide bleomycin is mediated by bleomycin hydrolase, a cysteine aminopeptidase identified in a variety of organisms. The opportunistic fungal pathogen Candida albicans is known to exhibit increased resistance to bleomycin when compared to other yeast. Presented here is the cloning of the C. albicans Lap3p aminopeptidase, predicted by sequence identity to be the Candida form of bleomycin...

Author(s): Alexandra R. Rogers, Stephanie M. Graves and Fernando Gonzalez