April 2012
Role of retinoid mediated microphthalmia-associated transcription factor (MITF) in melanoma
Retinoic acid is the most effective therapeutic drug for the treatment of many types of cancer, including melanoma. All-trans retinoic acid (ATRA) increases the protein level of MITF in melanoma cells within 2 to 4 days (Chan, 2007), indicating that RA induced MITF plays a vital role in its anti-proliferative action. On the contrary, MITF silencing can induce senescence in melanoma cells. These two...
April 2012
Erythromelalgia in a patient treated with penicillin
Erythromelalgia is a rare neurovascular peripheral disorder of unknown cause that affects hands or feet causing painful skin redness in affected area. The attacks are periodic and are commonly triggered by heat, pressure, mild activity, exertion, insomnia or stress. Erythromelalgia can occur either as a primary or idiopathic disorder, or as secondary forms associated with hematologic diseases. Drugs have...
April 2012
Chronic care model for diabetics by pharmacist home health in Bangkok Metropolitan: A community based study
Diabetes was increased in Thailand with increasing burden of morbidity and mortality. There were 42.8% of diabetes patients in Bangkok who had been treated, but the disease conditions were uncontrolled. Diabetes with drug related problems (DRPs) frequently occurred, leading to problems of uncontrolled disease conditions. The objective of this study was to apply chronic care model (CCM) which has been...
April 2012
Biological evolution of tryptophan and phenylalanine in the occurrence of breast cancer in Senegalese women
The reports provided by OMS in 2011 revealed that cancer is a major cause of death worldwide, causing 7.6 million deaths in 2008. Breast cancer represents in the world, the most common malignancy of women, and it seems that the low penetrance genes, frequently mutated in the general population would play an important role in the development of this cancer. The purpose of this study is to evaluate the...
April 2012
Nutritional assessment of the diets in rickets prevalent communities in Kaduna State of Nigeria
Absorption (SHIMADZU MODEL 650) was used to determine the levels of calcium and phosphorus in the food samples. Wet digestion method was adopted for the food samples preparation. The results obtained showed that calcium levels in all foods were low with mean values of 0.056±0.02, 0.069±0.04 and 0.127±0.06 mg\kg (S.E.M) in Gonin Gora, Jankasa and Kaso respectively. Phosphorous levels were...
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