December 2018

Cystatin C protection of human umbilical vein endothelial cell against oxidative stress injury through activating autophagy

Cystatin C (CysC)-induced autophagy may play a beneficial role in preventing subarachnoid hemorrhage-induced cerebral vasospasm. The role of CysC in endothelial cells (ECs) autophagy is unknown. This study explores the role of CysC during the process of oxidative stress in human umbilical vein endothelial cells (HUVECs). Oxidized LDL (oxLDL) was used to stimulate HUVECs in vitro study. The lactate dehydrogenase (LDH)...

Author(s): Wenjing Fan, Wenyi Deng, Tingting Tang, Yuning Zhu, Chi Zhang, Zhisheng Jiang and Shunlin Qu