May 2011

Effects of Hibiscus asper leaves extracts on carrageenan induced oedema and complete Freund’s adjuvant-induced arthritis in rats

The present study was undertaken to assess the anti-inflammatory potential of the aqueous and methanolic extracts of Hibiscus asper Hook. f. leaves (Malvaceae)  against carrageenan induced acute inflammation and complete Freund’s adjuvant (CFA)-induced arthritis in Wistar albino rats. In the carrageenan-induced acute inflammation, the methanolic extract of H. asper exhibited significant...

Author(s): Foyet Harquin Simplice, Abdou Bouba Armand, Ponka Roger, Asongalem Acha Emmanuel, Kamtchouing Pierre and Nastasa Veronica

May 2011

Implication of hydrogen peroxide in biochemical and morphological alterations of cultured adventitial fibroblasts of Psammomys obesus

Oxidative stress causes hypertrophy and apoptosis, which are both implicated in various pathogenesis, particularly in cardiovascular diseases. Within this framework, we chose toanalyze certain physiopathological aspects (lipid peroxidation, proliferation, extracellular matrix remodeling, hypertrophy and oncosis conducting the cell to...

Author(s): Boumaza S., Neggazi S., Hamlat N., Sahraoui H., Berdja S., Smail L., Kacimi G., Gernigon T., Benazzoug Y., and Aouichat  Bouguerra S.