October 2022
GSTM1 and T1 null variants effects on the predisposition to type 2 diabetes mellitus in Turabah population, Saudi Arabia
Type 2 diabetes mellitus (T2DM) is characterized by chronic hyperglycemia and associated with an increased production of reactive oxygen species (ROS) affecting beta cells in pancreas. Glutathione S- transferases (GSTs) are a family of antioxidant enzymes that include several classes of GSTs. These enzymes have important roles in decreasing ROS species and act as a kind of antioxidant defense. In a case-control study,...